Posaconazole Intermediate POA CAS 149809-43-8 Factory High Quality

Short Description:

Name: Posaconazole Intermediate POA

CAS: 149809-43-8

Appearance: White to Grey White Powder

Purity: ≥99.0%

Intermediate of Posaconazole (CAS 171228-49-2) Triazole Antifungal Agent

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Send email to us

Product Detail

Product Tags

Description:

Factory Supply Posaconazole Related Intermediates, Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2

Chemical Properties:

Name	Posaconazole Intermediate POA
Synonyms	(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester; (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate
CAS Number	149809-43-8
CAT Number	RF-PI291
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C21H21F2N3O4S
Molecular Weight	449.47
Density	1.40
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Grey White Powder
Identification	IR In accordance with the standard
Melting Point	100.0-102.0℃
Specific Rotation [a]20/D	-40.0° to -48° (C=1, CHCl3)
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Heavy Metals	≤20ppm
Related Substances
Major Impurity	≤0.40%
POA-Enantiomer	≤0.10%
POA-Diastereomer	≤0.20%
Individual Unknown Impurity	≤0.20%
Total Impurities	≤1.0%
Purity	≥99.0%
Assay	98.0%~102.0% (anhydrous substance)
Test Standard	Enterprise Standard
Usage	Intermediate of Posaconazole (CAS 171228-49-2)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester (CAS 149809-43-8) is the Intermediate of Posaconazole (CAS 171228-49-2). Posaconazole is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.