Pyrazinamide CAS 98-96-4 Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Pyrazinamide (CAS: 98-96-4) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
Chemical Name | Pyrazinamide |
Synonyms | Pyrazinecarboxamide; Pyrazinoic Acid Amide |
CAS Number | 98-96-4 |
CAT Number | RF-PI2156 |
Stock Status | In Stock, Production Capacity 20 Tons/Month |
Molecular Formula | C5H5N3O |
Molecular Weight | 123.11 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Crystalline Powder |
Purity / Analysis Method | >99.0% (HPLC) |
Purity / Analysis Method | 99.0~101.0% (Titration) |
Melting Point | 188.0~192.0℃ |
Water (By K.F) | <0.50% |
Heavy Metals | ≤10ppm |
Sulfated Ash | <0.10% |
Infrared Spectrum | Conforms to Structure |
Solubility in H2O | Colorless, Clear, 50 mg/mL in H2O Pass |
Single Impurity | <0.50% |
Total Impurities | <1.00% |
Test Standard | USP 37 Standard |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
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Pyrazinamide (CAS: 98-96-4) is a second-line anti-tuberculosis drug. It has a good antibacterial effect against human type Mycobacterium tuberculosis with the strongest bactericidal effect at the range of pH value being between 5-5.5. It has especially optimal bactericidal effect against the Mycobacterium tuberculosis inside the slow-growing phagocytic cells in acidic environment. After pyrazinamide penetrates into the phagocytic cells and enter into the body of Mycobacterium tuberculosis, lactamase in vivo make it be de-amidated, being converted to pyrazine acid to play the antibacterial effect. Pyrazinamide was synthesized in 1952, and it is the nitrogen-analog of nicotinamide. Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance. Pyrazinamide is an essential component of the multidrug short-term therapy of tuberculosis. In combination with isoniazid and rifampin, it is active against the intracellular organisms that may cause relapse.
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