(R)-(+)-1,1′-Bi-2-naphthol CAS 18531-94-7 Assay ≥99.5% (HPLC) e.e≥99.5% High Purity

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(R)-(+)-1,1'-Bi-2-naphthol (CAS: 18531-94-7) is obtained through resolution of racemic BINOL, which is usually made from 2-naphthol catalyzed by iron(III) chloride through radical reaction. (R)-(+)-1,1'-Bi-2-naphthol has been widely used for various applications: 1) chiral inducing agents for catalytic, asymmetric reactions such as the Diels-Alder reaction,ene reaction,or as Lewisacids; 2) enantioselective reduction of ketones; 3) synthesis of chiral macrocyclesand otherinteresting compounds. A chiral binapthol imminium salt precursor used in the catalytic asymmetric oxidation of sulfides to sulfoxides. Chiral lanthanide triflates formed from binaphthol serve as catalysts for asymmetric Diels-Alder reactions. Derivatives of binaphthol have recently been used in asymmetric Claisen rearrangements and asymmetric epoxidations. The lithium aluminum hydride derivative of these diols (BINAP-H) has been used extensively for the reduction of ketones. It is used in biosynthetic preparation for enantioselective oxidation of naphthols to binaphthyldiols with horseradish peroxidase catalyst.