(R)-Diphenylprolinol CAS 22348-32-9 Purity ≥99.0% e.e ≥99.0% Dapoxetine Hydrochloride Intermediate Factory

Short Description:

Chemical Name: (R)-Diphenylprolinol

CAS: 22348-32-9

Appearance: White Crystal

Purity: ≥99.0% e.e: ≥99.0%

Intermediate of Dapoxetine Hydrochloride (CAS: 129938-20-1) in the treatment of Premature Ejaculation in Men (PE)

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Product Detail

Product Tags

Description:

Commercial Supply Dapoxetine Hydrochloride and Related Intermediates:
3-Chloropropiophenone CAS: 936-59-4
(S)-3-Amino-3-Phenylpropan-1-ol CAS: 82769-76-4
(S)-3-Amino-3-Phenylpropanoic Acid CAS: 40856-44-8
(R)-Diphenylprolinol CAS: 22348-32-9
(S)-Diphenylprolinol CAS: 112068-01-6
(S)-(-)-3-Chloro-1-Phenyl-1-Propanol CAS: 100306-34-1
Dapoxetine Hydrochloride CAS: 129938-20-1

Chemical Properties:

Chemical Name	(R)-Diphenylprolinol
Synonyms	(R)-(+)-α,α-Diphenyl-2-Pyrrolidinemethanol;(R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine; (R)-(+)- α,α-Diphenylprolinol; (R)-1,1-Diphenylprolinol; (R)-(+)-Diphenyl-2-Pyrrolidinemethanol
CAS Number	22348-32-9
CAT Number	RF-CC114
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C17H19NO
Molecular Weight	253.35
Solubility in Chloroform	Almost Transparency
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White Crystal
Identification	HPLC; IR
Purity	≥99.0%
e.e	≥99.0%
Specific Rotation [α]_D²⁰	+66.0°~ +68.0° (C=3, MeOH 25℃)
Melting Point	77.0~81.0℃
Loss on Drying	≤0.50%
Single Impurity	≤0.50%
Total Impurities	≤1.0%
Heavy Metals	≤20ppm
Test Standard	Enterprise Standard
Usage	Chiral Compounds; Pharmaceutical Intermediates

Package & Storage:

Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-Diphenylprolinol (CAS: 22348-32-9) with high quality. Shanghai Ruifu Chemical Co., Ltd. plays an important role in the chiral chemistry, the company is committed to the production of chiral compounds. Our products are widely praised by customers.

(R)-Diphenylprolinol (CAS 22348-32-9) can be used in the synthesis of Dapoxetine Hydrochloride (CAS 129938-20-1). Dapoxetine Hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation (PE) in men. PE is the most common male sexual disorder.

(R)-Diphenylprolinol (CAS 22348-32-9) is the (R)-enantiomer of Diphenylprolinol, a relatively mild norepinephrine-dopamine reuptake inhibitor. (R)-α,α-Diphenylprolinol is more pharmacologically active than its (S)-enatiomer. (R)-Diphenylprolinol can be used for the preparation of the corresponding oxazolidine borane, the compound can be used for borane-mediated asymmetric reduction of ketone.