Rabeprazole Sodium CAS 117976-90-6 Purity >99.5% (HPLC) API Factory

Short Description:

Chemical Name: Rabeprazole Sodium 

CAS: 117976-90-6 

Purity: >99.5% (HPLC)  

White to Slightly Pale Yellow Crystal or Powder

API, Anti-Ulcer, Proton Pump Inhibitor

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name Rabeprazole Sodium 
Synonyms 2-([4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl]methylsulfinyl)-1H-Benzo[d]imidazole; Pariprazole
CAS Number 117976-90-6
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C18H20N3NaO3S
Molecular Weight 381.42
Melting Point 140.0~141.0℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Slightly Pale Yellow Crystal or Powder; Hygroscopic
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
ICP Confirms Sodium Component 
Solubility Completely Soluble in Water; Very Soluble in Ethanol, Chloroform; Soluble in Methanol
pH 9.5~12.0
Loss on Drying <1.00%
Heavy Metals <20ppm
Related Substances (HPLC)
Impurity A <0.80%
Unspecified Impurities <0.20%
Total Impurities <1.00%
Residual Solvents (GC)
Methylene Chloride <600ppm
Ethanol <5000ppm
Isopropyl Ether <5000ppm
Acetone <5000ppm
Microbial Limit
Aerobe Count ≤1000CFU/g
Mold and Yeasts Count ≤100CFU/g
E. Coli Absent for per gram
Purity / Analysis Method >99.5% (HPLC, Dried Basis)   
Test Standard Enterprise Standard
Usage API for Anti-Ulcer

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

Rabeprazole Sodium (CAS: 117976-90-6) is a proton pump inhibitor that suppresses gastric acid production in the stomach. It has several medical uses: the management of conditions that involve excess gastric acid production (e.g. Zollinger-Ellison syndrome), conditions that are worsened by gastric acid (e.g. ulcerations of the gastrointestinal tract), and conditions involving prolonged exposure to gastric acid (e.g. symptomatic gastroesophageal reflux disease). Rabeprazole is also useful alongside antibiotic therapy for the treatment of the pathogen Helicobacter pylori, which otherwise thrives in acidic environments. Thus, Rabeprazole Sodium is FDA approved for the treatment of symptomatic GERD in adolescents and adults, healing duodenal ulcers in adults, eradication of Helicobacter pylori, and pathologic hypersecretory conditions. Rabeprazole Sodium suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell.

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