Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory High Purity

Short Description:

Chemical Name: Rapamycin; Sirolimus; RAPA

CAS: 53123-88-9

Appearance: White or Off-White Crystalline Powder

Assay: ≥98.5%

Macrolide Immunosuppressive Agent

API High Quality, Commercial Production

E-mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer with High Purity and Stable Quality
Chemical Name: Rapamycin; Sirolimus; RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API High Quality, Commercial Production

Chemical Properties:

Chemical Name	Rapamycin
Synonyms	Sirolimus; RAPA; AY-22989
CAS Number	53123-88-9
CAT Number	RF-API59
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C51H79NO13
Molecular Weight	914.19
Melting Point	183.0~185.0℃
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Identification A	The IR spectrum of potassium bromide preparation of the sample exhibits maxima at the same wavelengths as that of a similar preparation of in-house reference standard
Identification B	The UV spectrum of 95% ethanol preparation of the sample exhibits maxima at 267nm, 277nm, 288nm as that of a similar preparation of in-house reference standard
Identification C	The retention time of the peaks for the trans-and cis-stereoisomers in the chromatogram of assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay
Optical Rotation	-147.0°~ -157.0°
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Heavy Metals	≤20ppm
Individual Impurity	≤1.5%
Total Impurities	≤2.0% (excluding Cis-Stereoisomer of Sirolimus)
Cis-Stereoisomer of Sirolimus	≤5.0%
Residual Solvents
Ethanol	≤5000ppm
Ethyl Acetate	≤5000ppm
Cyclohexane	≤5000ppm
Acetone	≤5000ppm
Diethyl Ether	≤5000ppm
Assay	≥98.5% (Calculated trans- and cis-stereoisomer of sirolimus on the dired basis)
Test Standard	Chinese Pharmacopoeia (CP); Enterprise Standard
Usage	Active Pharmaceutical Ingredient (API)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Rapamycin (Sirolimus; AY 22989) is is an autophagy activator, a new form of macrolide immunosuppressive agent with good curative effects, low toxicity, and no nephrotoxicity. It can be used to maintain the immunity of transplant organs (especially in kidney transplants) to alleviate immunological rejections after organ transplant surgeries.