Renewable Design for Idoxuridine - 3-Amino-1-Adamantanol CAS 702-82-9 Vildagliptin Intermediate – Ruifu

Manufacturer with High Purity and Competitive Price
Supply Vildagliptin and Related Intermediates:
Vildagliptin CAS: 274901-16-5
3-Amino-1-hydroxyadamantane CAS: 702-82-9
L-Prolinamide CAS: 7531-52-4
Boc-L-Proline CAS: 15761-39-4
(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile CAS: 207557-35-5

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 3-Amino-1-adamantanol (CAS: 702-82-9) with high quality. Vildagliptin is synthesised from 3-Amino-1-adamantanol.

Vildagliptin is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas. Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus. Novartis has since withdrawn its intent to submit vildagliptin to the FDA, as of July 2008. It was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions.