Rhein CAS 478-43-3 Purity >98.0% (HPLC)

Short Description:

Chemical Name: Rhein

Synonyms: Rhubarb Yellow; Rheic Acid; Monorhein

CAS: 478-43-3

Purity: >98.0% (HPLC)  

Extracted from Aloe Vera

Appearance: Fine Powder

Color: Orange or Yellow-Brown Needles   

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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478-43-3 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Rhein (Cassic Acid; Rhubarb Yellow; Rheic Acid; Monorhein) (CAS: 478-43-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Rhein, Please contact: alvin@ruifuchem.com

478-43-3 - Chemical Properties:

Chemical Name Rhein 
Synonyms Rhubarb Extract; Cassic Acid; Rhubarb Yellow; Rheic Acid; Monorhein; 4,5-Dihydroxyanthraquinone-2-Carboxylic Acid; 1,8-Dihydroxy-3-Carboxy Anthraquinone; 4,5-Dihydroxy-9,10-Dioxoanthracene-2-Carboxylic Acid; 4,5-Dihydroxy-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylate; 9,10-Dihydro-4,5-Dihydroxy-9,10-Dioxo-2-Anthracenecarboxylic Acid; 4,5-Dihydroxy-2-anthraquinonecarboxylic Acid; Chrysazin-3-Carboxylic Acid; Diacerein Impurity C
Stock Status In Stock, Commercial Production  
CAS Number 478-43-3
Molecular Formula C15H8O6
Molecular Weight 284.22 g/mol
Melting Point ≥300℃(lit.)   
λmax 432nm(MeOH)(lit.)
Sensitive Hygroscopic. Heat Sensitive 
Water Solubility  Insoluble in Water 
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

478-43-3 - Specifications:

Product Name: Rhein
CAS No:

478-43-3

Used Part:

Leaf

Plant Latin Name:      Aloe Vera Chemical name:

1,8-Dihydroxy-3-Carboxyanthraquinone

Batch Number:

RF-20131101

Manu. Date:

Nov. 01, 2013

Batch Size

100KG

Expiration Date:

Oct. 30, 2015

Net Weight:

10KG

Report Date

Nov 01, 2013

 

Item Specification Result Method
Maker Compounds ≥98.00% 98.76% HPLC
Organoleptic      
Appearance Fine Powder Conforms Visual
Color Orange or Yellow-Brown Needles  Conforms Visual 
Odor Characteristic Conforms Organoleptic
Taste Characteristic Conforms Organoleptic
Drying Method Vacuum drying Conforms  
Excipient None Conforms  
Physical Characteristics   
Particle Size ≥100% Through 80 Mesh Conforms GB5507-85
Loss on Drying ≦2.00% 0.50% GB/T12531-1990
Ash content ≦0.50% 0.03% AOAC942.05,17th
Bulk Density      
Pesticide Residue      
666 <0.20ppm Conforms GB/T5009.19-1996
DDT <0.20ppm Conforms GB/T5009.19-1996
Heavy Metals      
Total Heavy Metals ≤20ppm Conforms CP2000   IXE
Arsenic (As) ≤2.0ppm Conforms GB/T5009.11-1996
Lead (Pb) ≤2.0ppm Conforms GB/T5009.12-1996
Microbiological Tests   
Total Plate Count ≤1000cfu/g 435cfu/g AOAC990.12,16 th
Total Yeast & Mold ≤100cfu/g 60cfu/g FDA(BAM)Chapter18.8th Ed
E.Coli Negative Negative AOAC975.55,16 th
Salmonella Negative Negative FDA(BAM)Chapter5.8 th Ed
Staphylococcus Negative Negative AOAC
Conclusion: The product has been tested and complies with the given specifications 

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Stay away from strong light and heat, moisture. Incompatible with oxidizing agents. Heat sensitive.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

478-43-3 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes
36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
WGK Germany 2
RTECS CA9516000
HS Code 2918990090

478-43-3 - Application:

Rhein (Cassic Acid; Rhubarb Yellow; Rheic Acid; Monorhein) (CAS: 478-43-3) comes from rhubarb, aloe vera, polygonum multiflorum. Rhein has antitumor activity, antibacterial activity, immunosuppressive effect, diuretic effect, laxative effect, anti-inflammatory effect, treatment of diabetes and kidney disease. Health products are mainly used to lower fat and weight loss, laxative and detoxification, clean internal environment, prevent stomach cancer and delay aging.   

478-43-3 - Functions:

1. Rhein is shown to improve digestion and increase the appetite.
2. Rhein also helps heal ulcers, alleviate disorders of the spleen and colon, relieve constipation and help heal hemorrhoids and bleeding in the upper digestive tract.
3. Anti tumor activity and antibacterial activity also have immuno-suppression, cathartic and anti-inflammatory affection.
4. As the raw materials of drugs for cooling blood, detoxification and relaxing the bowels, Rhein is mainly used in pharmaceutical field; It has the functions of enhancing immunity, regulating gastrointestinal, anti-inflammatory, etc. It is a high-grade industry that can be used in health care products and medicines raw material.
5. As products for improving blood circulation and treating amenorrhea, Rheinis mainly used in health product industry.

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