Rifamycin S CAS 13553-79-2 Purity >97.5% (HPLC) Factory

Short Description:

Chemical Name: Rifamycin S

Synonyms: 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin

CAS: 13553-79-2

Purity: >97.5% (HPLC) 

Yellow or Orange Yellow Crystalline Powder

API High Quality Antibiotic Agent

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Rifamycin S (CAS: 13553-79-2) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Rifamycin S 
Synonyms 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin; Rifaximin EP Impurity E 
CAS Number 13553-79-2
CAT Number RF-PI2058
Stock Status In Stock, Production Capacity 500MT/Year 
Molecular Formula C37H45NO12
Molecular Weight 695.76
Sensitivity Heat Sensitive
Specific Rotation [α]20/D +451.0°~+500.0° (C=0.1 in MeOH)
Melting Point 201℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Yellow or Orange Yellow Crystalline Powder
Loss on Drying ≤3.00%(4h 100℃)
Residue on Ignition  ≤0.50%
Related Substances
Rifamycin-O ≤0.50%
Rifamycin-B ≤0.50%
One Peak ≤1.00%
Total Impurities ≤2.50%
Purity / Analysis Method >97.5% (HPLC)   
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Shelf Life 24 Months From Manufacture Date if Stored Properly
Usage A Key Intermediate for the Synthesis of Rifamycin Medicines

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

Rifamycin S (CAS: 13553-79-2) is a key intermediate for the synthesis of rifamycin medicines. Rifamycin S is a semi-synthetic antibiotic. Rifamycin S is a quinone and an antibiotic agnet against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy. The rifamycins are a group of chemically related antibioticsobtained by fermentation from cultures of Streptomycesmediterranei. They belong to a class of antibiotics called theansamycins that contain a macrocyclic ring bridged acrosstwo nonadjacent positions of an aromatic nucleus.  The rifamycins and many of their semisynthetic derivativeshave a broad spectrum of antimicrobial activity. They are most notably active against Gram-positive bacteriaand M. tuberculosis. However, they are also active againstsome Gram-negative bacteria and many viruses. Rifampin, asemisynthetic derivative of Rifamycin B, was released as anantitubercular agent in the United States in 1971. A secondsemisynthetic derivative, rifabutin, was approved in 1992 forthe treatment of atypical mycobacterial infections.

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