Rivaroxaban CAS 366789-02-8 Purity >99.5% (HPLC) Factory API High Quality
Manufacturer Supply Rivaroxaban Related Intermediates:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-one CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8
Chemical Name | Rivaroxaban |
Synonyms | (S)-Rivaroxaban; (S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carbox; BAY 59-7939 |
CAS Number | 366789-02-8 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C19H18ClN3O5S |
Molecular Weight | 435.88 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Almost White Powder |
Identification A | The infrared absorption of Rivaroxaban corresponds to reference standards |
Identification B | The retention time of the main peak of the sample solution corresponds to that of the system suitability solution ,as obtained in the enantiomeric purity. |
Enantiomeric Purity | RVX RC01: ≤0.15% |
Moisture (K.F) | ≤0.50% |
Sulphated Ash | ≤0.10% |
Heavy Metals | ≤20ppm |
Acetic Acid | ≤5000ppm |
Related Substances (HPLC) | |
RVX RC02 | ≤0.15% |
RVX RC03 | ≤0.15% |
RVX RC04 | ≤0.15% |
RVX RC05 | ≤0.15% |
RVX RC06 | ≤0.15% |
RVX RC07 | ≤0.15% |
RVX RC08 | ≤0.15% |
Any Other Individual Impurity | ≤0.10% |
Total Impurities | <0.50% |
Residual Solvents (GC) | |
Ethanol | ≤5000ppm |
Toluene | ≤890ppm |
Triethylamine | ≤320ppm |
Purity / Analysis Method | >99.5% (HPLC) (on anhydrous basis) |
Test Standard | Enterprise Standard |
Usage | API; Antithrombotic Drug; FXa Inhibitor |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Rivaroxaban (CAS: 366789-02-8) (Xarelto, Bayer) is an oral anticoagulant. It is an orally active direct factor Xa inhibitor. Rivaroxaban is indicated for the 'treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults'. For the initial treatment of acute pulmonary embolism, the recommended dosage of rivaroxaban is 15 mg twice daily for the first 21 days followed by 20 mg once daily for continued treatment and prevention of recurrent venous thromboembolism. Non-Valvular Atrial Fibrillation (NVAF) to prevent stroke & systemic embolism. Acute VTE treatment & prevention of recurrent VTE [for deep vein thrombosis (DVT) and pulmonary embolism (PE)]. Prevention of venous thromboembolic events (VTE) in elective total hip or knee replacement surgery (THR, TKR).