Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5%~102.0% API Factory High Purity
Supply with High Purity and Stable Quality
Rosuvastatin Calcium
CAS: 147098-20-2
Commercial Production
Chemical Name | Rosuvastatin Calcium |
Synonyms | ZD 4522 Calcium; (E)-6-[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate; (6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
CAS Number | 147098-20-2 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C44H54CaF2N6O12S2 |
Molecular Weight | 1001.14 |
Melting Point | 122℃ |
Shipping Condition | Shipped Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Off-White Powder |
Specific Rotation | +17.0° ~ +21.0° |
Identification | A. Meets the Requirement B. UV: λmax=243nm C. IR: Similar to Reference Substance D. X-Ray: Similar to Reference Substance |
Chloride | ≤0.10% |
Sulphate | ≤0.10% |
Enantiomer | ≤0.15% |
Calcium Content | 3.5%~4.5% |
Related Substances | |
Diastereomer | ≤0.15% |
5-Oxo-Rosucastatin | ≤0.15% |
Photo Degradation 1 | ≤0.15% |
Photo Degradation 2 | ≤0.15% |
Rosuvastatin Lactone | ≤0.15% |
Rosuvastatin Methyl Ester | ≤0.15% |
Rosuvastatin Isoamyl Ester | ≤0.15% |
Any Unknown Impurity | ≤0.10% |
Total Impurities | ≤0.75% |
Moisture (K.F) | ≤3.0% |
Heavy Metal | ≤20ppm |
Isoamyl Bromide | ≤37.5ppm |
Residual Solvents | |
Ethyl Ether | ≤300ppm |
Acetonitrile | ≤410ppm |
Isoamyl Alcohol | ≤5000ppm |
DMF | ≤880ppm |
Assay | 98.5%~102.0% (caculated on the anhydrous basis) |
Test Standard | Enterprise Standard; BP/USP/EP Standard |
Usage | API |
Package: Bottle, Barrel, Cardboard drum, 25kg/Barrel, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture
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Rosuvastatin Calcium (CAS: 147098-20-2) is an anti-hyperlipidemia drug which belongs to the inhibitor of HMG-CoA reductase successfully developed by the British AstraZeneca company. It is suitable for the treatment of various lipid abnormalities, including hypercholesterolemia, mixed lipid qualitative abnormalities and simple hypertriglyceridemia. Rosuvastatin Calcium (CAS: 147098-20-2) is listed as the strongest and the most comprehensive statins drugs which has entered into market for lipid-lowering and adjustment. Compared with atorvastatin which is currently recognized with the world's best efficacy, it has a better effect of lowering the level of LDL cholesterol and increasing the level of high-density lipoprotein. Moreover, it has a better tolerance, lower side effects and unique pharmacokinetic characteristics with the half-life about 20h.
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