(S)-(-)-1,1′-Bi-2-naphthol CAS 18531-99-2 Assay ≥99.0% (HPLC) e.e≥99.0% High Purity

Short Description:

Chemical Name: (S)-(-)-1,1′-Bi-2-naphthol

Synonyms: (S)-(-)-BINOL

CAS: 18531-99-2

Appearance: White Crystals or Crystalline Powder

Chiral Assay: e.e ≥99.0% (HPLC) Chiral Column

Chemical Assay: ≥99.0% (HPLC)

Chiral Compounds, High Quality, Commercial Production


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Description:

Chemical Properties:

Chemical Name (S)-(-)-1,1'-Bi-2-naphthol
Synonyms (S)-(-)-BINOL
CAS Number 18531-99-2
CAT Number RF-CC217
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C20H14O2
Molecular Weight 286.32
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Crystals or Crystalline Powder
Specific Rotation -33.5°~-38.0° (C=1 in THF)
Melting Point 208.0~210.0℃
Loss on Drying ≤0.50%
Chiral Assay e.e ≥99.0% (HPLC) Chiral Column
Chemical Assay ≥99.0% (HPLC) 
Test Standard Enterprise Standard
Usage Chiral Compounds; Pharmaceutical Intermediates 

Package & Storage:

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-(-)-1,1'-Bi-2-naphthol (CAS: 18531-99-2) with high quality, it belongs to pharmaceutical intermediate and can be used for the synthesis of chiral intermediates and chiral drugs.  

Shanghai Ruifu Chemical Co., Ltd. plays an important role in the chiral chemistry, the company is committed to the production of chiral compounds. Our products are widely praised by customers. 

(S)-(-)-1,1'-Bi-2-naphthol (CAS: 18531-99-2) is an organic compound that is often used as a ligand for transition-metal catalysed asymmetric synthesis. BINOL has axial chirality and the two enantiomers can be readily separated and are stable toward racemisation. The specific rotation of the two enantiomers is ±35.5° (C=1 in THF). BINOL is a precursor for another chiral ligand called BINAP. (S)-BINOL can be prepared directly from an asymmetric oxidative coupling of 2-naphthol with copper(II) chloride. The chiral ligand in this reaction is (S)-(+)-amphetamine. (S)-(-)-1,1'-Bi-2-naphthol (CAS: 18531-99-2) is used in the stereoselective synthesis of Peloruside A. Also used in the synthesis of BINAP-based aminophosphines and used for synthesis of various chiral reagents.

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