(S)-3-Hydroxy-γ-Butyrolactone CAS 7331-52-4 Purity >97.0% (GC) e.e >99.0% Factory

Short Description:

Chemical Name: (S)-3-Hydroxy-γ-Butyrolactone 

CAS: 7331-52-4

Purity: >97.0% (GC)  

Optical Purity: >99.0%  

Appearance: Colorless to Pale Yellow Liquid

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-3-Hydroxy-γ-Butyrolactone (CAS: 7331-52-4) with high quality, commercial production. Ruifu Chemical offers a wide range of chiral compounds. We can provide Certificate of Analysis (COA), worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name (S)-3-Hydroxy-γ-Butyrolactone
Synonyms (S)-β-Hydroxy-γ-Butyrolactone; (S)-3-Hydroxy-Gamma-Butyrolactone; (S)-(-)-3-Hydroxy-Gamma-Butyrolactone; S-HGB
CAS Number 7331-52-4  
CAT Number RF-CC344
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C4H6O3
Molecular Weight 102.09
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Colorless to Pale Yellow Liquid
Purity / Analysis Method >97.0% (GC)    
Optical Purity >99.0% e.e
Water Content (K.F) <0.20%
3,4-Di-OH-Butyric Acid <2.00%
Glycolic Acid <2.00%
Specific Rotation [α]20/D -80.0°~ -84.0° (C=2, Ethanol)
Specific Gravity (20/20℃) 1.3030~1.3090
Refractive Index n20/D 1.4620~1.4660
Infrared Spectrometry Conforms to Structure
Test Standard Enterprise Standard
Usage Chiral Building Blocks; Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

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FAQ:

Application:

(S)-3-Hydroxy-γ-Butyrolactone (CAS: 7331-52-4) is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S-oxiracetam (S-ORC). It can be deoxidized to (S)-(+)-3-Hydroxytetrahydrofuran which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-Hydroxy-4-Bromobutyric Acid which is a potential stabilizer. (S)-3-Hydroxy-γ-Butyrolactone is widely used in the pharmaceutical industry as a chiral building block for the statin class of cholesterol-reducing drugs such as Crestor and Lipitor, as well as the antibiotic Zyvox, and the antihyperlipidemic medication Zetia.

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