(S)-3-Hydroxypyrrolidine Hydrochloride CAS 122536-94-1 Purity ≥98.0% (GC) Darifenacin Hydrobromide Intermediate

Short Description:

Chemical Name: (S)-3-Hydroxypyrrolidine Hydrochloride 

CAS: 122536-94-1

Appearance: Off-White to Brown Crystalline Powder

Purity: ≥98.0% (GC)

Intermediate of Darifenacin Hydrobromide (CAS 133099-07-7) in the treatment of Overactive Bladder 

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer with High Purity and Competitive Price
Commercial Supply Darifenacin Hydrobromide Related Intermediates:
(S)-3-Hydroxypyrrolidine Hydrochloride CAS: 122536-94-1
(S)-α,α-Diphenyl-3-Pyrrolidineacetamide L-Tartrate CAS: 134002-26-9
(S)-2,2-Diphenyl-2-(Pyrrolidin-3-yl)acetonitrile Hydrobromide CAS: 194602-27-2
(S)-2,2-Diphenyl-2-(1-Tosylpyrrolidin-3-yl)acetonitrile CAS: 133099-09-9
2,3-Dihydrobenzofuran CAS: 496-16-2
2,3-Dihydrobenzofuranyl-5-Acetic Acid CAS: 69999-16-2
5-(2-Bromoethyl)-2,3-Dihydrobenzofuran CAS: 127264-14-6
Darifenacin Hydrobromide CAS: 133099-07-7

Chemical Properties:

Chemical Name (S)-3-Hydroxypyrrolidine Hydrochloride
Synonyms (S)-3-Hydroxypyrrolidine HCl; (S)-3-Pyrrolidinol Hydrochloride; (S)-Pyrrolidin-3-ol (Hydrochloride); (S)-Pyrrolidin-3-ol, HCl
CAS Number 122536-94-1
CAT Number RF-CC103
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C4H10ClNO
Molecular Weight 123.581
Melting Point 104°C to 107°C
Boiling Point 108°C to 110°C (8mmHg)
Solubility DMSO (Sparingly), Methanol (Slightly)
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Off-White to Brown Crystalline Powder
Chemical Purity  ≥98.0% (GC)
Specific Rotation +6.5° ~ +8.5° (C=3 CH3OH)
Any Individual Impurity ≤0.50%
Total Impurities ≤2.0%
Loss on Drying ≤0.50%
Residue on Ignition ≤0.50%
Test Standard Enterprise Standard
Usage Darifenacin Hydrobromide (CAS: 133099-07-7) Intermediate 

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to purchase?
Please contact: sales@ruifuchem.com 

QA (Quality Assurance)?
Reliable quality assurance, strict management. Professional equipment for analysis include NMR, LC-MS, GC-MS, HPLC, UPCC/HPLC, GC-HS, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Free Samples?
Free samples for quality evaluation available.

Factory Audit?
Factory audit welcome. Please make an appointment in advance.

MOQ?
No MOQ. Small order is acceptable.

Delivery time?
If within stock, three days delivery guaranteed

Transportation?
By Express(FedEx, DHL), by Air, by sea.

Custom Synthesis?
Can provide custom synthesis services.

Payment terms?
T/T(telex transfer), PayPal, Western Union, etc.

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis. (S)-3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) is the main intermediate of Darifenacin Hydrobromide (CAS: 133099-07-7).

Darifenacin Hydrobromide (CAS: 133099-07-7), an orally active, once a day selective M3 receptor antagonist, was launched for the treatment of overactive bladder in patients with symptoms of urge urinary incontinence, urgency and frequency. The drug selectively inhibits M3 receptor in the detrusor muscle while sparing the M1 and M2 receptors that are believed to be involved in central nervous system and cardiovascular function respectively. The compound was originally developed by Pfizer and licensed to Novartis and Bayer.

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