(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2 Purity > 99.0%(GC) Afatinib Amprenavir Fosamprenavir Intermediate

Short Description:

Chemical Name: (S)-3-Hydroxytetrahydrofuran

CAS: 86087-23-2

Colerless Transparent to Light Yellwow Liquid

Purity: >99.0%(GC) Optical Purity: >99.0% (GC)

Intermediate of Afatinib, Amprenavir, Fosamprenavir

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply; Hot Product; High Purity and Competitive Price
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
Afatinib CAS 439081-18-2, Afatinib Dimaleate CAS 850140-73-7 Main Intermediate
Amprenavir (CAS 161814-49-9) and Fosamprenavir (CAS 226700-79-4) Intermediate

Chemical Properties:

Chemical Name	(S)-3-Hydroxytetrahydrofuran
Synonyms	(S)-(+)-3-Hydroxytetrahydrofuran; (S)-Tetrahydrofuran-3-ol; (S)-(+)-Tetrahydro-3-Furanol
CAS Number	86087-23-2
CAT Number	RF-CC101
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C₄H₈O₂
Molecular Weight	88.11
Boiling Point	80℃/15 mmHg(lit.)
Density	1.103 g/mL at 25℃ (lit.)
Refractive Index	n20/D 1.45 (lit.)
Water Solubility	Soluble
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Colerless Transparent to Light Yellwow Liquid
Purity / Analysis Method	>99.0% (GC)
Identification	Retention time of the sample should match with the retention time of reference standard
Specific Rotation [α]_D²⁰	+17.5° ± 2.5° (C=2 in MeOH)
Optical Purity	e.e >99.0% (GC)
Moisture (K.F)	<0.50%
(R)-(-)-3-Hydroxytetrahydrofuran	<0.15%
Any Other Single Impurity	<0.40%
Total impurities	<1.00%
Test Standard	Enterprise Standard
Usage	IIntermediate of Afatinib, Afatinib Dimaleate, Amprenavir and Amprenavir Phosphate

(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2 ROS

Package & Storage:

Package: Bottle, Fluoride Barrels, 25kg/Barrel, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-(+)-3-Hydroxytetrahydrofuran (CAS: 86087-23-2) with high quality, widely used in the synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API). (S)-(+)-3-Hydroxytetrahydrofuran is the main intermediate of Afatinib (CAS 439081-18-2), Afatinib Dimaleate (CAS: 850140-73-7), Amprenavir (CAS 161814-49-9) and Fosamprenavir (CAS 226700-79-4). Afatinib (CAS 439081-18-2) is a potent, covalent/irreversible, and orally bioavailable dual (EGFR/ErbB) receptor tyrosine kinase (RTK) inhibitor with anticancer activity. Afatinib (CAS 439081-18-2) is a prescription medicine that can be taken orally for the treatment of non-small cell lung cancer (NSCLC) with atypical Epidermal Growth Factor Receptor (EFGR) agents. Amprenavir (CAS 161814-49-9) is a HIV protease inhibitor used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavi.