(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Mama ≥99.0% Bortezomib Intermediate Mama maualuga
Tuuina atu Bortezomib Fesoʻotaʻi Faʻatasi ma le Mama maualuga
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7
Igoa Vailaau | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
Synonyms | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
Numera CAS | 18680-27-8 |
CAT Numera | RF-CC290 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C10H18O2 |
Molecular Weight | 170.25 |
Solubility | Chloroform, Toluene |
Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e Pa'u |
Lisi Lisi | 56.0~59.0 ℃ |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.50% |
Enantiomeric Excess | ee≥99.0% |
Mama / Suʻesuʻega Metotia | ≥99.0% (GC) |
Ta'amilosaga Fa'apitoa [α]20/D | +8.5° i le +9.5° (C=6.5, Toluene) |
Alaleo Infrared | Fa'atatau |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Chiral Compounds;Vailaau Fa'atekonolosi;Bortezomib Intermediate |
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma tuʻuina atu (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) faʻatasi ai ma le maualuga maualuga, faʻaaogaina lautele i meaola. fa'asologa, fa'asologa o vaila'au vavalo ma vaila'au lelei.
Shanghai Ruifu Chemical Co., Ltd. faia se sao taua i le chiral kemisi, ua tuuto le kamupani i le gaosiga o chiral compounds.O a matou oloa e viia lautele e tagata faʻatau.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), o se mea aoga Chiral reagent o loʻo faʻaaogaina i le tuʻufaʻatasia o le homochiral α-hydroxyketones ma i le fofo o esters prolineboronate.Ose mea aoga fo'i muamua ile chiral allyl boronate o lo'o fa'aaogaina ile sauniuniga ole chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) o se Intermediate of Bortezomib (CAS 179324-69-7) i le togafitiga o le Myeloma Tele.O le Bortezomib, o le ubiquitin proteasome (26S) inhibitor malosi (Ki = 0.6 nM), na faʻalauiloaina i le US o se togafitiga mo le tele o myeloma.O lenei proteasome e manaʻomia mo le faʻaleagaina o le proteolytic o le tele o polotini feaveaʻi ma o loʻo i ai i sela uma.E mana'omia mo le fa'atonutonuina o faiga fa'ama'i, fa'atonuga o le ta'amilosaga o le sela ma le fa'aaliga o ga'o ma o se fa'amoemoe fou i togafitiga o le kanesa.