2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Mama >99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Tuuina atu o le Gaosi, Tulaga Maualuga ma Tau Fa'atauva
Tipiracil Hydrochloride (CAS: 183204-72-0) Fesoota'iga Vaitaimi
6-(Chloromethyl)uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
Igoa Vailaau | 2-Amino-1-Pyrroline Hydrochloride |
Synonyms | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
Numera CAS | 7544-75-4 |
CAT Numera | RF-PI1838 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C4H8N2·HCl |
Molecular Weight | 120.58 |
Lisi Lisi | 171.0 i le 175.0 ℃ |
Ma'ale'ale | Hygroscopic |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga | I'uga |
Fa'aaliga | Pa'u Pa'epa'e | Pa'u Pa'epa'e |
Mama / Suʻesuʻega Metotia | >99.5% (HPLC) | 99.8% |
Le Mama Nofofua Tele | <0.50% | 0.09% |
Suavai (KF) | <0.50% | 0.45% |
Proton NMR Alaleo | E tusa ai ma le Fauga | Fa'atatau |
Tulaga Su'ega | Pisinisi Tulaga | |
Fa'aoga | Vaitaimi ole Tipiracil Hydrochloride (CAS: 183204-72-0) |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
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2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) o le heterocyclic organic compound, lea e mafai ona faʻaaogaina e avea o se vailaʻau vavave.2-Amino-1-Pyrroline Hydrochloride o se vaeluaga ole Tipiracil Hydrochloride (CAS: 183204-72-0) ile togafitiga ole Kanesa Rectal.O le Tipiracil Hydrochloride o se fa'alavelave malosi ma fa'atauva'a o le thymidine phosphorylase (TPase) fa'atasi ai ma le IC50 tau o le 35 nM mo le TPase placental tagata.E filifilia mo TPase i luga o isi pyrimidine-metabolizing enzymes (IC50s => 1 mM mo UPase, OPRTase, TK, ma DPDase).TPI e taofia le phosphorolysis ma le faʻaleagaina o le trifluorothymidine, o le cytotoxic nucleoside, i le fatafata o le tagata ma faʻataʻitaʻiga tumo carcinoma colon.O le tautala tautala o le TPI (12.5-50 mg / kg) e faʻaleleia ai le gaioiga faʻafefe o le trifluorothymidine i se faʻataʻitaʻiga xenograft kanesa o le manava AZ-521.O fa'asologa o lo'o iai le TPI na fa'aaogaina mo le togafitia o le kanesa colorectal metastatic.