2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Mama ≥99.0% Pirfenidone Intermediate Factory
Manufacturer Sapalai, Mamalu Maualuga, Gaosiga Faapisinisi
Igoa vaila'au: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5
| Igoa Vailaau | 2-Hydroxy-5-Methylpyridine |
| Synonyms | 5-Methyl-2(1H)-Pyridinone;2-Hydroxy-5-Picoline;6-Hydroxy-3-Picoline;5-Methyl-2-Pyridinol |
| Numera CAS | 1003-68-5 |
| CAT Numera | RF-PI549 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C6H7NO |
| Molecular Weight | 109.13 |
| Lisi Lisi | 183.0 i le 187.0 ℃ (malamalama) |
| Solubility | Solu i le Methanol |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e-Pa'epa'e i le Pa'u tioata samasama |
| Mama | ≥99.0% |
| Susū (KF) | ≤0.50% |
| Toega i luga o le mumu | ≤0.50% |
| So'o se Fa'aleaga Ta'itasi | ≤0.50% |
| Aofa'i Fa'aleaga | ≤1.00% |
| Solvents totoe | |
| n-Butanol | ≤0.30% |
| Ethanol | ≤0.30% |
| Tulaga Su'ega | Enterprise Standard |
| Fa'aoga | Intermediate of Pirfenidone (CAS: 53179-13-8) |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) o loʻo faʻaaogaina e avea o se vailaʻau vaʻaia ole Pirfenidone (CAS: 53179-13-8).Pirfenidone (PFD) o se ituaiga fou o pyridine ketones o loʻo i ai le lautele o alaleo anti-fibrotic aafiaga, e mafai ona puipuia ma fesuiaʻi le faʻavaeina o fibrosis ma maʻila.Na ulufale i le maketi i Shionogi, Iapani i le 2008 ma ua faʻamaonia e le US Food and Drug Administration.Ole vaila'au muamua lea na fa'ata'ita'iina ile vaega III fa'ata'ita'iga (e aofia ai le toe fai, fa'avasegaina, ma le placebo-control) lea na fa'aalia ai lona aoga i le togafitia o le idiopathic pulmonary fibrosis (IPF);e le gata i lea, o le vailaʻau e iai lona aoga lelei i le togafitia o nisi faʻamaʻi fibrotic e pei ole fibrosis interstitial renal ma fibrosis ate.
