2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory Tulaga Maualuga Maualuga
Gaosiga Tuuina atu, Tulaga Maualuga, Gaosiga Fa'apisinisi
Tolvaptan ma Fesoota'iga Fa'atatau:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-tasi CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Igoa Vailaau | 2-Methyl-4-Nitrobenzoic Acid |
Synonyms | 4-Nitro-o-Toluic Acid;4-Nitro-2-Methylbenzoic Acid |
Numera CAS | 1975-51-5 |
CAT Numera | RF-PI397 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C8H7NO4 |
Molecular Weight | 181.15 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Toeitiiti Pa'epa'e po'o Pale Samasama Pa'u tioata |
1H-NMR | Ia ogatasi ma le Fauga |
Mama / Suʻesuʻega Metotia | ≥98.0% (HPLC) |
Lisi Lisi | 153.0~156.0 ℃ |
Susū (KF) | ≤0.50% |
Toega i luga o le mumu | ≤0.50% |
Aofa'i Fa'aleaga | ≤2.0% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Intermediate of Tolvaptan (CAS 150683-30-0) |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) o loʻo faʻaaogaina e avea o se vailaʻau faʻapitoa i le faʻaogaina o Tolvaptan (CAS 150683-30-0).Tolvaptan o se fili, faʻatauvaa arginine vasopressin receptor 2 antagonist faʻatasi ma le IC50 o le 1.28μM mo le faʻasaina o le faʻapipiʻiina o platelet aggregation AVP.Tolvaptan e faʻaaogaina e togafitia ai le hyponatremia (maualalo le toto sodium maualuga) e fesoʻotaʻi ma le faʻaletonu o le fatu, cirrhosis, ma le maʻi o le hormone antidiuretic le talafeagai (SIADH).Tolvaptan na fa'amaonia e le US Food and Drug Administration ia Me 19, 2009, ma fa'atau atu e le Otsuka Pharmaceutical Co. i lalo o le igoa tau fefa'ataua'iga Samsca.