(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Darunavir Intermediate High Purity
Faumea Faumea Sapalai Darunavir Oloa Fa'atatau:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Igoa Vailaau | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| Synonyms | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;Darunavir Intermediate |
| Numera CAS | 98737-29-2 |
| CAT Numera | RF-PI286 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C15H21NO3 |
| Molecular Weight | 263.33 |
| Solubility | E le mafai ona solu i le Vai.Solu i le Methanol, Chloroform |
| Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
| Fa'ailoga (HPLC) | O le Fa'ailoga ua Fa'amaonia e le HPLC |
| Lisi Lisi | 123.0~128.0 ℃ |
| Susū (KF) | ≤0.50% |
| Toega i luga o le mumu | ≤0.20% |
| Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
| Chlorohydrin (HPLC) | ≤0.20% |
| Chloromethyl Ketone | ≤0.10% |
| Isi Le Mama Nofofua | ≤0.20% |
| Aofa'i Fa'aleaga | ≤1.0% |
| Chiral Le mama | ≤0.30% |
| Metala mamafa | ≤20ppm |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma tuʻuina atu (2S,3S) -1,2-Epoxy-3-(Boc-Amino) -4-Phenylbutane (CAS: 98737-29-2) faʻatasi ai ma tulaga maualuga. , o se vaeluaga masani i le tuʻufaʻatasia o Darunavir (CAS 206361-99-1) ma Darunavir Ethanolate (CAS 635728-49-3).
Darunavir (CAS 206361-99-1) ose ituaiga fou ole peptide anti retroviral protease inhibitors ile AIDS therapy.E muamua fausia e le Johnson pharmaceutical Iceland lala, Tibotec.E sili ona maualuga le bioavailability i le 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir ma ABT378/r).E galue e ala i le taofia o le fausiaina o siama fou ma matutua mai luga o sela o loʻo aʻafia ma taofia ai le protease a le siama.A faʻaaogaina le oloa mo se taimi umi, e masani lava e mafai ona faʻaitiitia le siama HIV i totonu o le toto, faʻateleina le numera o sela CD4, faʻaitiitia le avanoa e maua ai le HIV, faʻaleleia le lelei o le olaga ma faʻaumiumi le ola.E talafeagai mo tagata matutua o loʻo aʻafia i le HIV ae leai se aafiaga i le faʻaaogaina o vailaʻau faʻamaʻi o loʻo iai.O le vailaʻau e tatau ona tuʻufaʻatasia ma le faʻaogaina o tui maualalo o ritonavir poʻo isi vailaʻau antiretroviral, ina ia faʻaleleia ai le aoga.
