3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Fa'amama Fa'atetele>98.0% (HPLC)
Ruifu Chemical o le taʻutaʻua taʻutaʻua o le 3-Nitrophthalic Anhydride (CAS: 641-70-3) faʻatasi ai ma le maualuga, vaeluaga o Pomalidomide (CAS: 19171-19-8).Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau 3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | 3-Nitrophthalic Anhydride |
| Synonyms | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dione;4-Nitroisobenzofuran-1,3-Dione;4-Nitro-1,3-isobenzofurandione;Pomalidomide le mama A |
| Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
| Numera CAS | 641-70-3 |
| Fuafua mole | C8H3NO5 |
| Molecular Weight | 193.11 g/mol |
| Lisi Lisi | 161.0 i le 165.0 ℃ |
| Ma'ale'ale | Susū ma'ale'ale |
| Suavai Solubility | E mafai ona pala i le vai |
| COA & MSDS | Avanoa |
| Amataga | Shanghai, Saina |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Tulaga Fa'atonu | I'uga |
| Fa'aaliga | Samasama moli i le nila samasama tioata po'o le pauta tioata | E usitaia |
| Lisi Lisi | 161.0~165.0 ℃ | 163.0~165.0 ℃ |
| Ma'imau ile Fa'amago | <0.50% | 0.10% |
| Mama / Suʻesuʻega Metotia | >98.0% (HPLC) | 98.85% |
| Alaleo Infrared | O gatasi ma le Fauga | E usitaia |
| 1H NMR Alaleo | O gatasi ma le Fauga | E usitaia |
| Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
| Fa'atatauga | Intermediate of Pomalidomide (CAS: 19171-19-8) | |
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Fa'ailoga Mata'utia Xi - Itaita
Tulaga lamatia
36/37/38 - Fa'aitaita'i i mata, faiga fa'alenava ma le pa'u.
Fa'amatalaga Saogalemu
S26 - Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga faafoma'i.
S36 - Fa'aofu ofu puipui talafeagai.
S37/39 - Fai totigilima talafeagai ma mata/mata puipui
WGK Siamani 3
FLUKA BRAND F CODES 10-21
TSCA Ioe
HS Code 2917399090
3-Nitrophthalic Anhydride (CAS: 641-70-3) o loʻo faʻaaogaina e avea o se vaeluaga o Pomalidomide (CAS: 19171-19-8).Ia Fepuari 2013, na faʻamaonia ai e le US FDA le Pomalidomide mo le togafitia o le tele o myeloma (MM) i tagata mamaʻi o loʻo faʻasolosolo faʻamaʻi pe a uma ona maua isi togafitiga o le kanesa.Pomalidomide o se 4-amino analog o le thalidomide ma faʻaleleia le malosi ma se faʻaleleia atili o faʻamatalaga oona.O le Pomalidomide ma le thalidomide e faʻaaogaina o latou aʻafiaga e ala i le faʻaogaina o le puipuiga, faʻasaina o le angiogenesis, faʻalavelave i le ponaivi / tumo microenvironment, ma le faʻasaina o le cereblon protein.Pomalidomide malosi faʻalavelave faʻateleina in vitro i le tele o laina cell MM tagata, IC50 ~ 10 nM, ae o le thalidomide na faʻaalia toetoe lava leai se faʻalavelave e oʻo atu i le 100 μM.I faʻataʻitaʻiga tumo MM mouse, 50 mg / kg doses i aso taʻitasi o le pomalidomide na iʻu ai i le faʻailogaina o le faʻalavelaveina o le tuputupu aʻe o le tuma pe a uma le 15 aso o togafitiga ma toe faʻamaeʻaina i le 3-6 vaiaso faʻasaga i le thalidomide-treated controls i le fua tutusa.Pomalidomide ua saunia e ala i le condensation o le 3-Nitrophthalic Anhydride ma le 3-Aminopiperidine-2,6-Dione sosoo ai ma le catalytic hydrogenation o le vaega nitro.
