3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Intermediate Factory
Mamalu Maualuga, Gaosiga Faapisinisi
Olaparib ma isi fa'atatau:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Igoa Vailaau | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| Synonyms | Dimethyl 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
| Numera CAS | 61260-15-9 |
| CAT Numera | RF-PI453 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C10H11O5P |
| Molecular Weight | 242.17 |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e po'o Toeitiiti Pa'epa'e Pa'epa'e |
| Mama | ≥98.0% |
| Susū (KF) | ≤0.50% |
| Aofa'i Fa'aleaga | ≤2.0% |
| Tulaga Su'ega | Enterprise Standard |
| Fa'aoga | Vaitaimi ole Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), vaeluaga o Olaparib (CAS: 763113-22-0).Olaparib o se ituaiga poly ADP-ribose polymerase (PARP) inhibitors, e aofia ai PARP1, PARP2, ma PARP3.E fa'atalanoaina e le PARP se masini toe fa'aleleia DNA lea e iai sona sao taua i le toe fa'aleagaina o le DNA ma le apoptosis, o lea e fa'atatau tonu ai le olaparib i le fa'afouga o le DNA o le fa'aleleia o le DNA o lo'o tulimata'i ma fa'atupu ai a'afiaga e ala i le osofa'ia o fa'afitauli ogaoga o sela o le kanesa o lo'o tauaveina suiga i BRCA1 ma BRCA2.Ona o lenei faiga, e mafai ona faʻaaogaina mo togafitiga faʻaleleia o tagata mamaʻi o loʻo maua i le kanesa ovarian maʻi tigaina o loʻo i ai le faʻafitauli o le kanesa o le susu (BRCA) faʻapea foi ma le maʻaleʻale i vailaʻau o le platinum.
