4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Mama>99.0% (HPLC) Almotriptan Aniline Precursor Factory
Ruifu Sapalai Vailaau Matautia Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Igoa Vailaau | 4- [(1-Pyrrolidinylsulfonyl)methyl]aniline |
Synonyms | 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor |
Numera CAS | 334981-10-1 |
CAT Numera | RF-PI1948 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C11H16N2O2S |
Molecular Weight | 240.32 |
Lisi Lisi | 170.0 i le 176.0 ℃ |
Malosi | 1.31 |
Solubility | E solu teisi ile Toluene |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le vaivai samasama tioata pauta |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Ma'imau ile Fa'amago | <0.50% |
Toega i luga o le mumu | <0.50% |
Max nofofua le mama | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Metala mamafa | <20ppm |
Alaleo Infrared | E tusa ai ma le Fauga |
NMR | E tusa ai ma le Fauga |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Almotriptan Aniline Precursor |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
4- [(1-Pyrrolidinylsulfonyl) methyl]aniline (CAS: 334981-10-1) o se vaeluaga i le sauniuniga o Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.Almotriptan Malate o se ituaiga o vailaʻau triptan e mafai ona faʻaaogaina mo togafitiga o le ulu ulu.Almotriptan o lo'o a'afia i se vaega o vaila'au o vaila'au fa'ato'aga fa'atosina o le serotonin.Almotriptan o loʻo i ai se maualuga ma faʻapitoa faʻatasi mo le serotonin 5-HT receptors, e oʻo atu ai i le vascoconstriction o le vaʻa toto o le faiʻai ma aʻafia ai le toe tufatufaina atu o le tafe toto.O nei a'afiaga e taofia ai fa'ailoga tiga mai le lafo atu i le fai'ai, ma fa'apena atili ai le fa'asa'olotoina o nisi o mea fa'alenatura e mafua ai le tiga, faufau ma isi fa'ailoga o le migraine.Ae ui i lea, e le taofia e Almotriptan osofaiga o migraine.Almotriptan, maketiina i le 2000, o loʻo i ai le maualuga o le oralbioavailability i totonu o triptans uma.Almotriptan e metabolized e MAO-A ma le CYP3A4, ma e sili atu ona lelei aʻafiaga aʻafiaga pe a faʻatusatusa i Sumatriptan.