4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatinib Mesylate Intermediate Purity >99.0% (HPLC)

4-Amino-3-Chlorophenol (CAS: 17609-80-2) o se vailaʻau taua tele, lea e faʻaaogaina lautele i le mamanu ma le tuʻufaʻatasia o anti-tumor, maʻi cardiovascular, faʻamaʻi faʻamaʻi faʻamaʻi.4-Amino-3-Chlorophenol o se mea taua tele i le sauniuniga o le Lenvatinib Mesylate (CAS: 857890-39-2).Na atiaʻe e Eisai Inc., lenvatinib mesylate o se vascular endothelial growth factor receptor (VEGF) inhibitor o loʻo i ai le gaioiga e faasaga i le VEGF subtypes 1, 2, ma le 3 ma na faʻatagaina e le FDA i le 2015 mo le togafitiga o le kanesa thyroid eseese lea e faʻapitonuʻu. faifai pea, metastatic, poʻo le alualu i luma ma e leʻi tali atu i togafitiga iodine radioactive.I le masina o Me 2016, na faʻamaonia ai e le FDA le vailaʻau e avea o se togafitiga faʻatasi ma everolimus mo le togafitiga o le gasegase o le tino.Talu ai ona o le VEGF (ma le fibroblast growth factor receptors, ua taʻua o FGFRs) e manatu e faia se sao i ala cardiovascular signaling, o le VEGF2R ma le FGFR inhibition o loʻo manatu o auala ia i tua atu o aʻafiaga muamua o le lenvatinib mesylate, o le toto maualuga.