4-Dimethylaminopyridine DMAP CAS 1122-58-3 Mama> 99.0% (HPLC) Fa'atosina maualuga
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o le 4-Dimethylaminopyridine (DMAP) (CAS: 1122-58-3) ma le maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, laʻititi ma tele aofaʻi avanoa.Fa'atau DMAP, Please contact: alvin@ruifuchem.com
Igoa Vailaau | 4-Dimethylaminopyridine |
Synonyms | DMAP;4-(Dimethylamino)pyridine;N-(4-Pyridyl)dimethylamine;N,N-Dimethylpyridin-4-Amine;N,N-Dimethyl-4-Pyridinamine;gamma-(Dimethylamino)pyridine |
Numera CAS | 1122-58-3 |
Tulaga Fa'asoa | I Fa'atauga, Gaosi Gaosi 40 Tone i le Masina |
Fuafua mole | C7H10N2 |
Molecular Weight | 122.17 |
Lisi Lisi | 110.0~114.0 ℃ |
Fa'apuna | 190 ℃/150 mmHg |
Malosi | 0.906 g/mL ile 25℃ |
Fa'asino Upu | n20/D 1.431 |
Solubility i le Methanol | Mata'utia Lega |
Solubility i le Vai | Solu i le Vai, 80 g/l 25 ℃ |
Solubility (Soluble i totonu) | Chloroform, Benzene, Methanol, Acetone |
COA & MSDS | Avanoa |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Lisi Lisi | 110.0~114.0 ℃ |
E le mafai ona soloia i le vai | <0.10% |
Susū (KF) | <0.30% |
Ma'imau ile Fa'amago | <0.50% (I lalo ole Vacumn Mo le 3 Itula ile 60ºC) |
Le mama nofofua | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Alaleo Infrared | Ia ogatasi ma le Fauga |
1 H NMR Alaleo | Ia ogatasi ma le Fauga |
Tulaga Su'ega | Pisinisi Tulaga |
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1122-58-3 - Tulaga lamatia ma le Saogalemu
Tulaga lamatia
R25 - Oona pe a foloina
R34 - Mafua ai mu
R24/25 -
R36/37/38 - Fa'aitaita'i i mata, faiga manava ma le pa'u.
R27 - Oona tele pe a fa'afeso'ota'i ma pa'u
R36 - Fa'aitaita i mata
R24 - Oona pe a pa'i ma pa'u
R20 - E afaina pe a manava
R61 - E ono afaina ai le pepe e le'i fanau mai
R40 - Fa'amaoniga fa'atapula'a o se a'afiaga tuga
R23/24/25 - Oona pe a manava, fa'afeso'ota'i ma pa'u ma pe a foloina.
R67 - O ausa e ono mafua ai le tulemoe ma le niniva
R66 - Fa'aalia fa'afia e ono mago pe ta'e le pa'u
R21/22 - E afaina pe a pa'i i le pa'u ma pe a foloina.
R11 - Sili ona mu
R36/37 - Fa'aitaita i mata ma le manava.
R22 - E afaina pe a foloina
R19 - E mafai ona fa'atupu ai ni peroxide papa
Fa'amatalaga Saogalemu
S36/37/39 - Fai ofu puipui talafeagai, totigilima ma mata/mata.
S45 - I se fa'alavelave fa'afuase'i pe ua e lagona le le lelei, saili vave fautuaga fa'afoma'i (fa'aali le igoa pe a mafai.)
S28A -
S26 - Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga faafoma'i.
S28 - A uma ona pa'i i le pa'u, fufulu vave i le tele o fasimoli.
S36/37 - Fai ofu puipui ma totigilima talafeagai.
S53 - Aloese mai le fa'aalia - maua fa'atonuga fa'apitoa a'o le'i fa'aogaina.
S27 - Aveese vave uma lavalava ua pisia.
S22 - Aua le manava pefu.
S16 - Tausia mai mea e mu ai.
UN ID UN 2811 6.1/PG 2
WGK Siamani 3
RTECS US8400000
TSCA T
HS Code 2942000000
Mata'utia Fa'amatalaga Oona/A'a
Vasega o lamatiaga 8
Vaega fa'apipi'i II
Oona LD50 tuugutu ile Lapiti: 140 mg/kg LD50 dermal Lapiti 90 mg/kg
4-Dimethylaminopyridine (DMAP) (CAS: 1122-58-3) o se faʻamalosi fou sili ona lelei e faʻaaogaina lautele i vailaʻau faʻasolosolo.O loʻo i ai le malosi maualuga o le catalytic i le faʻaogaina o meaola, faʻasologa o vailaʻau, vailaʻau faʻamaʻi, vali, manogi manogi o le acylation, alkylation, etherification ma isi ituaiga o tali, ma e iai sona aafiaga manino i le faʻaleleia o fua.Acylation o le ava malosi;Acylation o phenols;Acylation o amine;Acylation o enolates;Tali a isocyanates;Talosaga Eseese;Fa'aliliuina o Vaega Fa'atino.
DMAP, o se super nucleophilic acylation catalyst.O le resonance o le electron-donating dimethylamino vaega i lona fausaga ma le mama matua (pyridine mama) e mafai ona malosi faʻagaoioia le nitrogen atom i luga o le mama e faʻafeiloaʻi ai le nucleophilic substitution, lea e matua faʻamalosia ai le maualuga o le teteʻe, maualalo-reactive alcohols ma amines / acids Le gaioiga. o le acylation / esterification tali e tusa ma le 104 ~ 106 taimi o le pyridine.Acyl transfer o se suiga masani i le natura ma le faʻaogaina o meaola, lea o le chiral DMAP o se faʻasologa masani asymmetric acyl transfer catalyst.Talu mai le 1996, Vedejs ma Fu 'au na lipotia le ogatotonu chiral ma planar chiral DMAP catalysts faasologa, chiral DMAP catalysts ua matua atiina ae.Ole tele ole chiral tutotonu, planar chiral, spiro chiral ma central chiral DMAP ua lipotia tasi ma le isi, ma ua lelei ona faʻaogaina i le tele o asymmetric acyl transfer reactions.
O le DMAP o se faʻamalosi nucleophilic sili ona lelei mo gaioiga faʻafefe ma esterifications.O loʻo faʻaaogaina foi i suiga eseese o meaola e pei o le Baylis-Hillman reaction, Dakin-West reaction, puipuiga o amine, C-acylations, silylations, talosaga i mea faʻalenatura kemisi, ma le tele o isi.
E mafai ona fa'aogaina le DMAP e fai ma fa'amalosi: Mo le acylation o 'ava mālosi fa'atasi ai ma acid anhydride i lalo o fa'avae fesoasoani- ma tulaga e leai se solvent e fa'apipi'i ai esters tutusa.I le tali a Baylis-Hillman e fausia ai le carbon-carbon bond e ala i le fa'apipi'iina o se alkene fa'agaoioia ma se aldehyde po'o le ketone.
O se faʻamalosi sili ona lelei mo gaioiga acylation.