5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Intermediate Mama ≥99.0%
Tuuina atu le Vonoprazan Fumarate ma le Intermediate Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Igoa Vailaau | 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde |
| Synonyms | Vonoprazan Fumarate (TAK-438) Intermediate 3 |
| Numera CAS | 881674-56-2 |
| CAT Numera | RF-PI330 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C11H8FNO |
| Molecular Weight | 189.19 |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Samasama i le Enaena Pata |
| Lisi Lisi | 122.0~131.0 ℃ |
| Fa'ailoa: RT(HPLC) | Fa'atasi ma le Fa'asinomaga Tulaga |
| Ma'imau ile Fa'amago | ≤0.50% |
| Toega i luga o le mumu | ≤0.50% |
| Mea Fa'atatau | |
| Mama | ≥99.0% |
| So'o se Fa'aleaga Ta'itasi | ≤0.50% |
| Aofa'i Fa'aleaga | ≤1.0% |
| Tulaga Su'ega | Enterprise Standard |
| Fa'aoga | Intermediate of Vonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
5-(2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) galue e pei o se reagent i le saunia synthetic o tala fou pyrrole derivatives e pei o le potassium-competitive acid blocker (P-CAB).5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde ole vaeluaga ole Vonoprazan Fumarate (CAS 1260141-27-2).Vonoprazan fumarate (Takecab®), na maua ma atiina ae e Takeda ma Otsuka, na faʻamaonia e le PMDA o Iapani ia Tesema 2014, ma faʻaalia mo togafitiga o le gastric ulcer, duodenal ulcer ma reflux esophagitis.O le Vonoprazan fumarate o loʻo i ai se faiga fou o gaioiga e taʻua o le potassium-competitive acid blockers, lea e faʻatauvaʻa faʻalavelave ai le fusifusia o ion potassium i le H +, K + -ATPase (faʻapitoa foi o le pamu proton) i le laasaga mulimuli o le faʻamalo o le gatric acid i totonu o sela parietal gastric.E le taofia e Vonoprazan le gaioiga o le Na +, K + -ATPase e oʻo lava i faʻatonuga 500 taimi maualuga atu nai lo latou IC50 faʻatatau ile gastric H +, K + -ATPase gaioiga.E le gata i lea, o le vailaʻau e le afaina i le gastric secretory state, e le pei o PPI.
