5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Manufacturer Sapalai, Mamalu Maualuga, Gaosiga Faapisinisi
Dapagliflozin (CAS: 461432-26-8) Fesoʻotaʻiga Faʻatasi:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
Igoa Vailaau | 5-Bromo-2-Chlorobenzoic Acid |
Synonyms | 2-Chloro-5-Bromobenzoic Acid |
Numera CAS | 21739-92-4 |
CAT Numera | RF-PI439 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C7H4BrClO2 |
Molecular Weight | 235.46 |
Lisi Lisi | 154.0 i le 156.0 ℃ (malamalama) |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e-Pa'epa'e i le Pa'u Samasama Malamalama |
Su'ega | ≥99.0% |
Vai (KF) | ≤0.50% |
Toega i luga o le mumu | ≤0.30% |
2-Chlorobenzoic Acid | ≤0.30% |
2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
Aofa'i Fa'aleaga | ≤1.0% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Vaeluaga o Dapagliflozin (CAS: 461432-26-8), ituaiga II maʻisuka |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) o loʻo faʻaaogaina e fai ma mea amata i le tuʻufaʻatasiga o Dapagliflozin (CAS: 461432-26-8), o le sodium-glucose cotransporter-2 inhibitor filifilia e faʻaitiitia ai fatugao. kulukose reabsorption ma e fa'aaogaina e togafitia ai gasegase e maua i le ma'isuka ituaiga II.Dapagliflozin o se malosi ma filifili SGLT-2 (SLC5A2) faʻalavelave faʻatasi ma le EC50 o le 1.1 nM.O lo'o i ai le fa'afefeteina lelei i luga o membranes cell Caco-2 ma o se mea e fa'aogaina mo le P-glycoprotein (P-gp).Dapagliflozin na faʻamaonia i le 2012 e le FDA.