6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Tuuina atu ma le mama maualuga, gaosiga faapisinisi
Igoa Vailaau: 6-O-Methylguanine
CAS: 20535-83-5
| Igoa Vailaau | 6-O-Methylguanine |
| Synonyms | 2-Amino-6-Methoxypurine |
| Numera CAS | 20535-83-5 |
| CAT Numera | RF-PI509 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C6H7N5O |
| Molecular Weight | 165.16 |
| Lisi Lisi | >300℃ (malamalama) |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'u Pa'epa'e Pa'epa'e |
| Su'ega / Su'esu'ega Metotia | ≥98.5% (HPLC) |
| Ma'imau ile Fa'amago | ≤0.50% |
| Toega i luga o le mumu | ≤0.50% |
| Aofa'i Fa'aleaga | ≤1.5% |
| Tulaga Su'ega | Enterprise Standard |
| Fa'aoga | Intermediate of Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
6-O-Methylguanine (CAS: 20535-83-5) e mafai ona faʻaaogaina e avea o se vaeluagalemu i le tuʻufaʻatasiga o Nelzarabine (CAS: 121032-29-9).Nelarabine o se prodrug mo deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates i le matafaioi o le adenosine deaminase (ADA) ma liliu i le ara-G.Nelarabine na muamua faʻaleleia lelei e GlaxoSmithKline.O Oketopa 28, 2005 i lalo o le faamaoniga a le US Food and Drug Administration, na avea ma fualaau fou mo le togafitia o le leukemia lymphoblastic T-cell (T-ALL) ma le T-Cells lymphoblasticlymphoma (T-LBL) lea e tetee atu i le itiiti ifo. lua ituaiga o chemotherapy regimens pe toe fa'afo'i pe a uma togafitiga muamua.O lenei fualaau faasaina fou na lisiina aloaia i le Iunaite Setete i le 2006.
