7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-tasi CAS 160129-45-3 Tolvaptan Intermediate
Gaosiga Tuuina atu, Tulaga Maualuga, Gaosiga Fa'apisinisi
Tolvaptan ma Fesoota'iga Fa'atatau:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-tasi CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Igoa Vailaau | 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-tasi |
Synonyms | 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-tasi;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-tasi |
Numera CAS | 160129-45-3 |
CAT Numera | RF-PI395 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C10H10ClNO |
Molecular Weight | 195.65 |
Lisi Lisi | 103.0 i le 107.0 ℃ |
Solubility | Solu i le Methanol |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Malamalama lanumeamata i le pauta samasama malamalama |
Faiga Fa'ailoa | NMR, HPLC |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
Ma'imau ile Fa'amago | ≤1.0% |
Toega i luga o le mumu | ≤0.50% |
So'o se Fa'aleaga Ta'itasi | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Intermediate of Tolvaptan (CAS 150683-30-0), togafitiga o le Hyponatremia |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
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7-Chloro-1,2,3,4-tetrahydrobenzo [b] azepin-5-one (CAS 160129-45-3) o se vaeluagalemu i le tuufaatasiga o Tolvaptan (CAS 150683-30-0).Tolvaptan ose fa'atauva'a fa'atauva'a fa'atauva'a nonpeptide arginine vasopressin V2 fa'afeagai tali fa'atasi ma le IC50 o le 1.28µM mo le fa'alavelaveina o le fa'apipi'iina o platelet avg.Tolvaptan e faʻaaogaina e togafitia ai le hyponatremia e fesoʻotaʻi ma le faaletonu o le fatu fatu, cirrhosis, ma le maʻi o le hormone antidiuretic le talafeagai.Tolvaptan o loʻo i ai foʻi i suʻesuʻega faʻataʻitaʻi vave mo faʻamaʻi fatugaʻo polycystic.Togafitiga ma Tolvaptan e mafua ai le faʻaitiitia o le mamafa o le tino faʻafuaseʻi faʻatasi ma le faʻateleina o le urine, faʻaleleia ma / poʻo le faʻamalieina o le sodium serum i tagata mamaʻi hyponatremic, faʻaitiitia faʻailoga ma faʻamaoniga o le pipii ma faʻateleina le fia inu.