7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Mama>99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Fa'amatalaga Puupuu:

Igoa: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Mama: >99.0% (HPLC)

Fa'aaliga: Samasama Malamalama e Pa'u Eenaena Malamalama

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Auina imeli ia matou

Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

Fa'amatalaga:

Ruifu Sapalai Vailaau Fa'alava ole Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-tasi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Meatotino tau vailaau:

Igoa Vailaau	7-Chloro-6-Nitro-4-Hydroxyquinazoline
Synonyms	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-tasi;7-Chloro-6-Nitroquinazolin-4(3H)-tasi
Numera CAS	53449-14-2
CAT Numera	RF-PI2030
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole	C8H4ClN3O3
Molecular Weight	225.59
Ma'ale'ale	Ma'ale'ale vevela
Solubility	Laititi solu i le Dimethylformamide
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Samasama Malamalama i le Pata Enaena Malamalama
Fa'ailoga (HPLC)	Taimi Fa'atumauina o Fa'ata'ita'iga e Tatau Ona Fa'atusa ma Fa'atonu
Mama / Suʻesuʻega Metotia	>99.0% (HPLC)
Lisi Lisi	300.0~303.0 ℃
Suavai (KF)	<0.50%
Toega i luga o le mumu	<0.30%
Le mama 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Le mama 2	<0.50% (5,7-Dichloro-4[1H]quinazolinone)
Le mama 3	<1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
Isi Le Mama Nofofua	<0.20%
Aofa'i Fa'aleaga	<1.00%
Metala mamafa (pei o le Pb)	<20ppm
Alaleo Infrared	E tusa ma le Fauga
Proton NMR Alaleo	Proton NMR Alaleo
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	Intermediate of Afatinib, Afatinib Dimaleate

Paket & Teuina:

afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

Tulaga lelei:

FAQ:

Talosaga:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) o se vaeluaga ole Afatinib Dimaleate (CAS: 850140-73-7).O le Afatinib o se aiga ErbB e le mafai ona toe fa'afo'isia o poloka e taofia ai le tu'uina atu o fa'amatalaga ma poloka ai ala tetele e a'afia i le tuputupu a'e ma le vaevaeina o sela o le kanesa.Talu ai e mafai ona fa'aosoina e le tele o homodimers ma heterodimers le fa'aogaina o fa'amatalaga a le aiga ErbB, o le fa'alavelave fa'atasi o le tele o tagata o le aiga ErbB (e pei o le EGFR, HER2, ErbB3 ma le ErbB4) e mafai ona fa'alavelave lelei le fa'aliliuina o fa'amatalaga i lalo.O le Afatinib e fa'aaogaina e togafitia ai se ituaiga o kanesa o le mama (kanesa o le tino e le o ni sela laiti) lea ua sosolo atu i isi vaega o le tino.E a'afia i se vasega o vaila'au e ta'ua o le iniseti kinase.E galue e ala i le faʻagesegese pe taofi le tuputupu aʻe o sela o le kanesa.E fusifusia i se polotini (epidermal receptor-EGFR) i nisi tuma.