7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate Mama maualuga
Faumea Faumea Sapalai Irinotecan ma Fesoota'iga Fa'atatau:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Igoa Vailaau | 7-Ethyl-10-Hydroxycamptothecin |
Synonyms | SN-38 |
Numera CAS | 86639-52-3 |
CAT Numera | RF-PI242 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C22H20N2O5 |
Molecular Weight | 392.41 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u tioata lanu samasama samasama mama |
Fa'ailoa (IR, UV) | (1) Ole alaleo ole absorption ave ole Ultraviolet e ogatasi ma manaoga (2) E tatau ona tausisia le fusi o alaleo o le ave infrared e ogatasi ma le fusi o alaleo masani ma suesuega faamaonia. |
Lisi Lisi | 228.0~235.0 ℃ |
Mea Fa'atatau | ≤1.5% |
10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Avanoa Le Malamalama Tele | ≤0.50% |
Ma'imau ile Fa'amago | ≤1.0% |
Metala mamafa | ≤10ppm |
Toega i luga o le mumu | ≤0.10% |
Malamalama ole Fofo | manino |
Su'ega | ≥98.0% (HPLC) |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Pharmaceutical Intermediate o Irinotecan |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
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Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o le 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) faʻatasi ai ma le maualuga.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) o se metabolite malosi o le Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) taofia DNA ma RNA fa'atasi ma IC50s o 0.077 ma 1.3 μM, faasologa.7-Ethyl-10-Hydroxycamptothecin (SN-38), o le metabolite malosi o Irinotecan, o se semisynthetic derivative o camptothecin, o se alkaloid faavae quinoline maua i le paʻu o le laau Saina camptotheca ma le laau nothapodytes Asia.E ui lava o le 7-Ethyl-10-Hydroxycamptothecin e oʻo atu i le 1,000 taimi e sili atu le malosi nai lo Irinotecan, e leʻi liua i se sui faʻatau fualaau faʻatau aua e le mafai ona faʻafefe.O lo'o fa'ata'ita'iina i le taimi nei i fa'ata'ita'iga fa'apitoa fa'atasi ma isi vaega e mafai ona fa'ataga ai lona aoga e avea o se vaila'au fa'ama'i.