7-Fluoro-6-Nitroquinazolin-4(1H)-tasi CAS 162012-69-3 Mama>99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Fa'amatalaga Puupuu:

Igoa Vailaau: 7-Fluoro-6-Nitroquinazolin-4(1H)-tasi

CAS: 162012-69-3

Mama: >99.0% (HPLC)

Samasama i le mumu samasama tioata po'o le pauta

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Tulaga Maualuga, Gaosiga Fa'apisinisi

E-Mail: alvin@ruifuchem.com

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Fa'amatalaga Oloa

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Fa'amatalaga:

Ruifu Sapalai Vailaau Fa'alava ole Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-tasi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Meatotino tau vailaau:

Igoa Vailaau	7-Fluoro-6-Nitroquinazolin-4(1H)-tasi
Synonyms	7-Fluoro-6-Nitroquinazolin-4(3H)-tasi;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-tasi
Numera CAS	162012-69-3
CAT Numera	RF-PI2025
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole	C8H4FN3O3
Molecular Weight	209.13
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Samasama i le mumu samasama tioata po'o le pauta
1 H NMR Alaleo	Osi ma le Fauga
Mama / Suʻesuʻega Metotia	>99.0% (HPLC)
Ma'imau ile Fa'amago	<0.50%
Aofa'i Fa'aleaga	<1.00%
Proton NMR Alaleo	E tusa ma le Fauga
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Paket & Teuina:

afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

Tulaga lelei:

FAQ:

Talosaga:

7-Fluoro-6-Nitroquinazolin-4(1H)-one (CAS: 162012-69-3) o se vaeluaga o Afatinib Dimaleate (CAS: 850140-73-7).O le Afatinib o se aiga ErbB e le mafai ona toe fa'afo'isia o poloka e taofia ai le tu'uina atu o fa'amatalaga ma poloka ai ala tetele e a'afia i le tuputupu a'e ma le vaevaeina o sela o le kanesa.Talu ai e mafai ona fa'aosoina e le tele o homodimers ma heterodimers le fa'aogaina o fa'amatalaga a le aiga ErbB, o le fa'alavelave fa'atasi o le tele o tagata o le aiga ErbB (e pei o le EGFR, HER2, ErbB3 ma le ErbB4) e mafai ona fa'alavelave lelei le fa'aliliuina o fa'amatalaga i lalo.Afatinib o se vailaʻau faʻamaonia mo le togafitiga e le o ni tamaʻi sela mama mama (NSCLC), na atiaʻe e Boehringer Ingelheim.E galue o se inhibitor angiokinase.E pei o le lapatinib ma le neratinib, o le afatinib o le tyrosine kinase inhibitor (TKI) lea e le mafai foi ona faʻalavelaveina le tagata epidermal growth factor receptor 2 (Her2) ma le epidermal growth factor receptor (EGFR) kinases.O le Afatinib e le gata ina malosi e tetee atu i suiga o le EGFR o loʻo faʻatatau i TKI o augatupulaga muamua e pei o le gefitinib poʻo le gefitinib, ae faʻapea foʻi ma i latou e le amanaʻia i nei togafitiga masani.Ona o lana gaioiga faaopoopo faasaga ia Her2, o loʻo suʻesuʻeina mo le kanesa o le susu faʻapea foʻi ma isi faʻamaʻi EGFR ma Her2.