7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Mama >99.0% (GC) Agomelatine Intermediate
Ta'ita'i Gaosi ma Fa'atauina Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Igoa Vailaau | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Synonyms | Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate |
| Numera CAS | 6836-21-1 |
| CAT Numera | RF2687 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C15H16O3 |
| Molecular Weight | 244.29 |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Suavai Malamalama Samasama Malamalama |
| Mama / Suʻesuʻega Metotia | >99.0% (GC) |
| Vai (saunia e Karl Fischer) | <0.50% |
| Mea Fa'atatau | <1.00% |
| Alaleo Infrared | E tusa ma le Fauga |
| NMR Alaleo | E tusa ma le Fauga |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Pharmaceutical Intermediate of Agomelatine (CAS: 138112-76-2) |
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) o se vailaʻau faʻapipiʻi gaogao aoga, e mafai ona faʻaaogaina e avea o se vailaʻau faʻapitoa ole Agomelatine (CAS: 138112-76-2).Agomelatine, lea na atiina ae e le kamupani Farani Servier, o le vaega muamua o le melatonin receptors MT1 ma MT2 agonist vasega o antidepressants i le lalolagi.E faʻatatau i le togafitiga o tagata matutua maʻi maʻi tigaina.Agomelatine o se vailaʻau faʻamaʻi.Agomelatine o se agonist o le melatonin (MT) talitali ma se mea e maua mai i le melatonin.E fusifusia i le MT1 ma le MT2 faʻafeiloaʻi (Kis = 0.14 ma le 0.41 nM, taʻitasi) ma o loʻo i ai le tau EC50 o le 0.1 nM i se [35S] GTPγS suʻega faʻaogaina e faʻaaoga ai sela CHO faʻaalia MT2 tali.O loʻo faʻavasegaina o se norepinephrine-dopamine disinhibitor (NDDI) ona o lona faʻalavelave o le 5-HT2C receptor.O le faʻagaoioia o 5-HT2C faʻafeiloaʻi e le serotonin e taofia ai le tuʻuina atu o le dopamine ma le norepinephrine.
