7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3 Mama >99.0% (HPLC) Agomelatine Intermediate
Ta'ita'i Gaosi ma Fa'atauina Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Igoa Vailaau | 7-Methoxy-1-Naphthylacetonitrile |
| Synonyms | 7-Methoxy-1-Naphthylmethylcyanide;7-Methoxy-1-Naphthaleneacetinitrile;1-Cyanomethyl-7-Methoxynaphthalene;2-(7-Methoxy-1-Naphthyl)acetonitrile;2-(7-Methoxynaphthalen-1-yl)acetonitrile;Agomelatine Le mama 12;Agomelatine Intermediate 1 |
| Numera CAS | 138113-08-3 |
| CAT Numera | RF2504 |
| Tulaga Fa'asoa | I Fa'atauga, Gaosi Gaosi 30 Tone i le Masina |
| Fuafua mole | C13H11NO |
| Molecular Weight | 197.24 |
| Lisi Lisi | 83.0 i le 86.0 ℃ |
| Malosi | 1.135±0.06 g/cm3 |
| Fa'asinoga Fa'asinomaga n20/D | 1.44 |
| Solubility | Solu i le Methanol |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pata Samasama Malamalama |
| Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
| Lisi Lisi | 83.0~86.0 ℃ |
| Ma'imau ile Fa'amago | <0.50% |
| Toega i luga o le mumu | <0.20% |
| Le mama nofofua | <0.50% |
| Aofa'i Fa'aleaga | <1.00% |
| Metala mamafa | <20ppm |
| Proton NMR Alaleo | E tusa ma le Fauga |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Vailaau Fa'atekonolosi;Agomelatine Intermediate |
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7-Methoxy-1-Naphthylacetonitrile (CAS: 138113-08-3) o se vaeluaga o Agomelatine (CAS: 138112-76-2).Agomelatine, lea na atiina ae e le kamupani Farani Servier, o le vaega muamua o le melatonin receptors MT1 ma MT2 agonist vasega o antidepressants i le lalolagi.Agomelatine e faʻaaoga i le togafitiga o tagata matutua maʻi maʻi tigaina.Agomelatine o se vailaʻau faʻamaʻi fou faʻatasi ai ma gaioiga agonist filifilia i tali melatonin ma faʻalavelave faʻafefe i le serotonin 5HT-2C receptors.E le afaina ai le faʻaogaina o le serotonin, noradrenaline poʻo le dopamine.E mafai ona fesoasoani le Agomelatine i le faatonutonuina o lou 'uati o lou tino' (circadian rhythm) ma aoga lelei i le lagona ma le atuatuvale o le moe E fa'aaogaina le Agomelatine i le togafitia o le atuatuvale po'o le fesoasoani e puipuia le toe fo'i mai o le atuatuvale, ma e na'o le avanoa e maua i le talavai a le foma'i.Agomelatine - Ma'i o le Mafaufau O le isi vasega "blockbuster" o fualaau faasaina.Agomelatine o loʻo i ai faʻamaʻi faʻamaʻi, anti-popole, fetuutuunai le pao moe ma faʻatonutonu le matafaioi a le uati olaola, ma ona faʻalavelave faʻaleagaina, faʻafeusuaiga e aunoa ma ni aʻafiaga leaga, ma leai se tali faʻamavae.Agomelatine ei ai sona aafiaga lelei i tagata mamaʻi ma le atuatuvale, ma o aʻafiaga leaga e laʻititi lava.Ole fua fautuaina mo Agomelatine e masani lava ole 25mg ile aso ile afa itula ao lei moe.
