S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0
Ruifu Chemical o le taʻutaʻua taʻutaʻua o le S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) faʻatasi ai ma le maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | S-Adenosyl-L-Methionine |
| Synonyms | Ademetionine;S-Adenosylmethionine;TUSI;SAM;AdoMet |
| Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
| Numera CAS | 29908-03-0 |
| Fuafua mole | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Lisi Lisi | 267.0~269.0 ℃ |
| Ma'ale'ale | Sili ona Hygroscopic |
| Suavai Solubility | Solu i le Vai |
| Sogisogi & Tofo | Uiga |
| COA & MSDS | Avanoa |
| Fa'ata'ita'iga | Avanoa |
| Amataga | Shanghai, Saina |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga | I'uga |
| Fa'aaliga | Toetoetoe lava paepae Pa'epa'e Lelei (Very Hygroscopic) | Fa'amaonia |
| Solubility | Solu i le Vai | |
| Fa'ailoaga | 1. Fa'aa'ai vaila'au | Tali lelei |
| 2. IR: O gatasi ma le fusi o alaleo na maua ile RS | Fa'amaonia | |
| 3. O le taimi fa'atumauina o se tumutumu tele e fa'amalieina mana'oga | Fa'amaonia | |
| Acid Value | 1.5~2.5 | 1.9 |
| Malamalama ma Lanu o le Fofo | E le sili atu ona lanu lanu nai lo le RS Y1 | Fa'amaonia |
| Vai saunia e Karl Fischer | ≤3.00% | 2.2% |
| Toega i luga o le mumu | ≤0.30% | 0.14% |
| Metala mamafa (Pb) | ≤10ppm | <10ppm |
| Endotoxin | ≤0.3EU/mg | Fa'amaonia |
| Microbiological | E tatau ona ausia le manaʻoga | |
| Faitauga o Papatusi Aofa'i | ≤1000cfu/g | 55cfu/g |
| Faafefete & Mold | ≤100cfu/g | 12cfu/g |
| E. Coli | Toesea/10g | E usitaia |
| S. Aureus | Toesea/10g | E usitaia |
| Salmonella | Toesea/10g | E usitaia |
| S-Adenosyl-L-Homocystein | ≤0.50% | 0.10% |
| Methithioadenosine | ≤1.00% | 0.24% |
| Adenine | ≤0.50% | 0.09% |
| Mea Fa'atatau | ||
| O Isi Fa'aleaga Tele | ≤0.20% | 0.01% |
| O Isi Aofa'i Aofa'iga | ≤0.50% | 0.006% |
| (S,S) Isomer | >62.0% | 79.4% |
| Butanedisulfonate | 46.0~49.0% (Fa'avae ile mago) | 47.5% |
| Ademetionine | 50.0~53.0% (Fa'avae ile mago) | 52.1% |
| Aofa'iga Aofa'iga | >97.5% (Fa'avae ile mago) | 99.6% |
| Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
| Ola Fa'asa | 2 Tausaga Pe a Teu Lelei | |
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R23 - Oona pe a manava
R34 - Mafua ai mu
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S23 - Aua le manava le ausa.
S36/37/39 - Fai ofu puipui talafeagai, totigilima ma mata/mata.
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HS Code 2934999099
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) o se mea faʻapipiʻi masani o loʻo aʻafia i le methyl group transfers.O le SAMe na maua muamua i Italia e GL Cantoni i le 1952, SAMe o se mole e gaosia i taimi uma e sela ola uma, e mafai ona puipuia le kanesa o le ate, faʻalauiloaina o le cartilaginous tissue forming ma concrescence, e mafai ona fesoasoani e tetee atu i le atuatuvale, faʻamaʻi Alzheimer, maʻi ate, ma le tiga o le. Osteoarthritis, SAMe ua fa'ailoaina fa'alelalolagi o se vaila'au taua e togafitia ai fa'ama'i ate.I aso nei o le SAMe e masani ona faʻaaogaina i vailaʻau, falemaʻi meaʻai tausiga soifua maloloina i maketi i totonu o le atunuʻu ma faavaomalo.O lo'o fa'atau atu le SAME i le Iunaite Setete e fai ma mea'ai fa'aopoopo.
1. S-Adenosyl-L-Methionine o se meaʻai lelei mo le ate, lea e mafai ona puipuia le ava malosi, fualaau faasaina ma le faaleagaina o le ate;
2. S-Adenosyl-L-Methionine ei ai se aafiaga puipuia taua i le hepatitis galue tumau ma isi mea e mafua ai le faaleagaina ate, fatu fatu, kanesa ma isi.
3. S-Adenosyl-L-Methionine ua maua e tutusa lelei ma vailaʻau mo le togafitia o le gugu ma le atuatuvale tele.
4. I totonu o le Iunaite Setete, ua fa'atau atu le SAM e fai ma mea'ai fa'aopoopo i lalo o le igoa maketi SAM-e (e sipelaina fo'i SAME po'o SAME).O nisi suʻesuʻega ua faʻaalia ai o le faʻaaogaina o le SAM e mafai ona fesoasoani e faʻafefe ai le atuatuvale, maʻi ate, ma le tiga o le osteoarthritis.Ole tele o su'esu'ega ile falema'i ua fa'aalia ai e lelei mo le fa'avaivai, fa'ama'i o le ate ma le osteoarthritis.O isi fa'ailoga uma e le'i fa'amaonia.
5. Fa'amanino fa'aoga e fa'aleleia ai le ga'oi o le ate.O le tu'ufa'atasiga ma le L-DOPA mo le togafitia o le ma'i o Parkinson e mafai ona fa'aleleia atili ai le aoga o le L-dopa ma fa'aitiitia ai a'afiaga.E mafai ona iloa le tiga i le lotoifale, popole le tumau ma le le mautonu i le nofoaga o tui.
O le S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) e iai foʻi aʻafiaga lelei ile gasegase, maso fibrous, migraine ma isi faʻamaʻi, ma e itiiti sona aʻafiaga.I le amataga o le 1970s, na faʻaaogaina le SAMe e fai ma vailaʻau faʻamaʻi mo le gasegase i Europa.I le 1999, na faʻamaonia ai e le US FDA le SAME o se oloa faʻalesoifua maloloina ma ua avea ma se tasi o meaʻai sili ona faʻatau atu i le Iunaite Setete.
S-Adenosyl-L-Methionine e masani lava ona saunia e ala i vailaʻau faʻasolosolo, faʻafefeteina ma suiga enzymatic.O le auala fa'afefeteina o le fa'aopoopoina lea o le L-Methionine muamua i le ala autu o lo'o i ai C ma N puna'oa, ma o se aofaiga tele o S-Adenosylmethionine e mafai ona maua e ala i le culturing sela microbial.Ole taimi nei ole auala autu mo le gaosiga o fale gaosi oloa ole S-Adenosylmethionine.Faatasi ai ma i latou, o microorganisms faʻaaogaina mo le faʻafefeteina e mafai ona maua e ala i le suʻesuʻeina poʻo le toe tuʻufaʻatasia o auala faufale, o loʻo faʻamauina i le tele o tala ma pateni i le fale ma fafo.O nisi suʻesuʻega ua tuʻuina atu ai se auala sauniuni o le S-adenosylmethionine, faʻaaogaina polyhydroxy organic reagents e puipuia ai le gaioiga o le enzyme, faʻaaogaina adenosine triphosphate precursor, L-Methionine ma phosphate ions e fai ma substrates, glucose poʻo / ma maltose e avea ma foaʻi malosi, faʻaopoopoina se tuufaatasiga o u'amea u'amea, ma le fa'aogaina o se fa'alumaina o le gaosiga e fa'atupuina le gaosiga o le S-Adenosylmethionine i sela atoa.Faʻaaogaina o le tuʻufaʻatasiga o ion uʻamea e faʻatonutonu ai le faʻaogaina o le metabolic e faʻaleleia ai le malosi o le faʻaogaina o le tagata lava ia, faʻaopoopoina mea faʻapitoa e puipuia ai le gaioiga o siama ma enzymes, faʻaaogaina se faʻalavelave faʻafefeteina e saunia ai le S-Adenosylmethionine, faʻapuupuu le taimi faʻapipiʻi, ma faia le oloa faʻaputu i fafo atu o le sela, lea e mafai ona faʻasaoina le tau o le teteʻa mulimuli ane ma faʻafaigofie laasaga o gaioiga.
O faʻamatalaga e uiga i le saogalemu umi o le S-Adenosyl-L-Methionine e faʻatapulaʻa ona o tagata na auai i le tele o suʻesuʻega na latou faʻaaogaina mo na o sina taimi puupuu.Ae ui i lea, i se suʻesuʻega se tasi o faʻamaʻi ate e aʻafia ai le ava, na ave e tagata auai le S-Adenosyl-L-methionine mo le 2 tausaga;i lena suʻesuʻega, e leai ni aʻafiaga ogaoga na lipotia.
O tagata e maua i le ma'i pipili (se ma'i e fa'aalia i suiga o lagona, mai le atuatuvale i le mania) e le tatau ona ave le SAMe mo o latou fa'afitauli fa'anoanoa se'i vagana i lalo o le vaavaaiga a se tausi soifua maloloina ona e ono fa'ateteleina e le SAMe auga o le mania.
E ui lava o le S-Adenosyl-L-Methionine na faʻaaogaina e togafitia ai le cholestasis i le taimi o le maitaga, o lona saogalemu i le taimi o le maitaga e leʻi faʻamautuina.
E mafai e le SAMe ona fa'aitiitia a'afiaga o le levodopa (L-dopa), o se vaila'au e fa'aaoga e togafitia ai le ma'i o Parkinson.E mafai fo'i ona fegalegaleai le SAME ma vaila'au ma mea'ai faaopoopo e fa'atuputeleina ai le maualuga o le serotonin (o se vaila'au e gaosia e sela neura), e pei o vaila'au fa'ama'i, L-tryptophan, ma St. John's wort.
O loʻo i ai se popolega faʻapitoa e uiga i le faʻaaogaina o le SAMe e tagata e le atoatoa (e pei oi latou e maua i le HIV).O tagata e le atoatoa le puipuiga e lamatia i le Pneumocystis carinii, ma o le SAMe e faʻaleleia ai le tuputupu aʻe o lenei microorganism.
O a'afiaga o le SAMe e le masani ai, ma pe a tupu e masani lava o ni fa'afitauli laiti e pei o le fa'aituau po'o le fa'afefe o mea'ai.
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