Afatinib Dimaleate Intermediate CAS 314771-88-5 Mama >99.0% (HPLC) Falegaosimea
Ruifu Sapalai Vailaau Fa'alava ole Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-tasi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5
Igoa Vailaau | (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-Amine |
Synonyms | N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl] oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl) amino-6-Nitroquinazoline;Afatinib le mama |
Numera CAS | 314771-88-5 |
CAT Numera | RF-PI2027 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C18H14ClFN4O4 |
Molecular Weight | 404.78 |
Malosi | 1.534±0.060 g/cm3 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama i le Pa'u Samasama Malamalama |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Ma'imau ile Fa'amago | <0.50% |
Le mama o le tagata lava ia | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Metala mamafa | ≤20ppm |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Intermediate of Afatinib Dimaleate (CAS: 850140-73-7) |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-Amine (CAS: 314771-88-5) o loʻo faʻaaogaina i le sauniuniga o Afatinib Dimaleate (CAS: 850140-73-7).O le Afatinib o se vailaʻau fou e faʻatatau i le kanesa, o se tupulaga fou o vailaʻau faʻatau gutu, o le vailaʻau faʻamaʻi faʻamaʻi muamua a le lalolagi e le mafai ona faʻaaogaina i le aiga ErbB, ma e sili atu ona aoga ma taulaʻi poloka le faailo e faʻaosoina ai le tuputupu aʻe o sela o le kanesa. , faʻaitiitia pe tuai le faʻateleina o sela o le kanesa.Afatinib e aofia i se vasega o vailaʻau e taʻua o tyrosine kinase inhibitors.E galue e ala i le polokaina o galuega a polotini vavalalata e lua, o le epidermal growth factor receptor (EGFR) ma le tagata epidermal growth factor receptor 2 (HER2).Fa'aaogaina mo le laina muamua o togafitiga o tagata mama'i e maua i le kanesa o le mama sela e le o ni metastatic.O le Afatinib o se vailaʻau fou e faʻatatau i le kanesa, o se tupulaga fou o vailaʻau faʻatau gutu, o le vailaʻau faʻamaʻi faʻamaʻi muamua a le lalolagi e le mafai ona faʻaaogaina i le aiga ErbB, ma e sili atu ona aoga ma taulaʻi poloka le faailo e faʻaosoina ai le tuputupu aʻe o sela o le kanesa. , faʻaitiitia pe tuai le faʻateleina o sela o le kanesa.