Anastrozole CAS 120511-73-1 API Falegaosimea Maualuga Maualuga
Tuuina atu a le Faumea ma le Mamalu Maualuga ma le Tulaga Lelei
Igoa vaila'au: Anastrozole
CAS: 120511-73-1
Igoa | Anastrozole |
Synonyms | Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
Numera CAS | 120511-73-1 |
CAT Numera | RF-API74 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C17H19N5 |
Molecular Weight | 293.37 |
Solubility | Solu i le DMSO ma le Ethanol |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
Faailoaina A | IR/MS Fa'atatau ile tulaga fa'asino |
Faailoaga B | HPLC ma foliga pito i luga: E fetaui ma faʻamatalaga |
Lisi Lisi | 81.0~84.0 ℃ |
Suavai (e KF) | ≤0.30% |
Toega i luga o le mumu | ≤0.10% |
Ma'imau ile Fa'amago | ≤0.50% |
Metala mamafa | ≤10ppm |
Mea Fa'atatau | |
Le mama A | ≤0.10% |
Le mama B | ≤0.20% |
Le mama C | ≤0.20% |
Le mama D | ≤0.10% |
Le mama E | ≤0.10% |
Nofofua Isi Le mama | ≤0.10% |
Aofa'i Fa'aleaga | ≤0.50% |
Solvents totoe | |
Cyclohexane | ≤0.30% |
Ethyl Acetate | ≤0.50% |
Su'ega | 98.0%~102.0% (i luga ole fa'amamago) |
Ola Fa'asa | 24 masina |
Tulaga Su'ega | Atina'e Atina'e;United States Pharmacopoeia (USP) Standard |
Fa'aoga | Togafitiga mo le Kanesa o le Fatafata |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
![1](https://www.ruifuchemical.com/uploads/15.jpg)
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Anastrozole (CAS 120511-73-1), o se non-steroidal, tolu-tupulaga achiral triazole derivative maketiina o ARIMIDEX® e AstraZeneca Pharmaceuticals LP1.O se tasi o le tolu-tupulaga aromatase inhibitor lea o se inhibitor sili ona tauva ma filifili o le aromatase, ma taofia ai le liua o le testosterone i estradiol ma androstenedione i estrone.O le taofiofia o le enzyme aromatase e tupu faapitoa lava e ala i le fusia faatauva o le aromatase i le hemegroup o le cytochrome P450, faʻaititia le estrogen biosynthesis i totonu o le tino o le tino ma le susu.
O le Anastrozole ose togafitiga masani mo le kanesa o le susu i le amataga.E pei o isi inhibitors aromatase, o lona aafiaga leaga sili ona taua o le faateleina o le lamatiaga o gau ponaivi, lea mo anastrozole na faʻatapulaʻaina i le vaitaimi o togafitiga.O lona uiga e itiiti lona o'ona pe a fa'atusatusa i le chemotherapy;ae ui i lea, ua maitauina le tele o tagata gasegase na togafitia i le anastrozole ua faitio i faʻailoga sooga nai lo le faʻamoemoeina, ae maise le maaa numera e tutusa ma le gasegase o le rheumatoid.O nisi o su'esu'ega fa'afoma'i o le anastrozole mo tama'ita'i ua mae'a le fa'ata'ita'iga e maua i le kanesa o le susu i Europa ma le Iunaite Setete na lipotia mai fa'aletonu musculoskeletal o ni mea leaga.Anastrozole (Arimidex®) o se inhibitor aromatase ua faamaonia i le EU, le US ma isi atunuu i le lalolagi atoa mo le faʻaaogaina o se togafitiga faʻapitoa i fafine postmenopausal ma le amataga, o le hormone receptor-positive breast cancer.Ua fa'atagaina fo'i i totonu ole EU ma isi atunu'u i le lalolagi atoa mo le fa'aauauina o togafitiga fa'apitoa i fafine ua uma ona maua le 2-3 tausaga ole fa'aogaina ole tamoxifen mo le kanesa o le susu.
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