Argatroban CAS 74863-84-6 API Falegaosimea Maualuga Mamalu Anticoagulant
Manufacturer Supply Argatroban Related Intermediates:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
| Igoa Vailaau | Argatroban |
| Synonyms | Argatroban Anhydrous |
| Numera CAS | 74863-84-6 |
| CAT Numera | RF-API67 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
| Fuafua mole | C23H36N6O5S |
| Molecular Weight | 508.63 |
| Lisi Lisi | 188.0~189.0 ℃ |
| Fa'apuna | 801.3ºC ile 760 mmHg |
| Malosi | 1.47 g/cm3 |
| Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
| Fa'ailoga HPLC | O le taimi fa'atumauina o le maualuga o mataupu faavae na maua mai le Su'ega fofo e ogatasi ma le mea na maua mai le vaifofo masani, e pei o le su'ega ile Assay |
| Faailoaina IR | E tusa ai ma le IR Spectrum o le AG RS |
| Fa'ailoga UV | I totonu ole 259nm ma le 332nm ole galu umi ole nofoaga e tatau ona i ai le maualuga ole absorption |
| Vai | 2.5-4.5% |
| Fofo Lanu & Malamalama | Fofo e tatau ona manino lanu |
| Fa'amatala mea | |
| Le mama A + le mama H | ≤0.10% |
| Le mama B | ≤0.10% |
| Le mama C + Le mama E | ≤0.10% |
| Le mama D | ≤0.10% |
| Le mama I | ≤0.10% |
| Bach o le le ma'oti le mama | ≤0.10% |
| Aofa'i Fa'aleaga | ≤0.30% |
| Solvents totoe | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Enantiomer (HPLC) | ≤0.10% |
| Fa'atusatusaga fa'aisomer (HPLC) | 30.0%-40.0% |
| Klorida | ≤0.01% |
| Toega i luga o le mumu | ≤0.10% |
| Metala mamafa | ≤10ppm |
| Endotoxins siama | <5EU/mg |
| Tapulaa Microbial | TAMC ≤1000 cfu/g |
| Su'ega | 98,0% -102,0% |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | API, Synthetic Antithrombotic Agent Anticoagulant |
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le faʻatauina o Argatroban (CAS: 74863-84-6) faʻatasi ai ma le maualuga, API.
Argatroban (CAS: 74863-84-6) o se sui fou synthetic antithrombotic aoga i le tausiga anticoagulation latou ischemic stroke ma faasalalauina intravascular coagulation.Ose anticoagulant ose mole laʻititi saʻo thrombin inhibitor.I le 2000, na laiseneina argatroban e le Food and Drug Administration (FDA) mo le puipuia poʻo le togafitia o le thrombosis i tagata mamaʻi e maua i le heparin-induced thrombocytopenia (HIT).I le 2002, na faʻatagaina mo le faʻaaogaina i taimi o faʻalavelave faʻalavelave faʻafuaseʻi i tagata mamaʻi e maua i le HIT pe o loʻo lamatia i le atiaʻe.I le 2012, na faʻamaonia e le MHRA i Peretania mo le faʻamaʻiina o tagata mamaʻi i le heparin-induced thrombocytopenia Type II (HIT) o loʻo manaʻomia le togafitiga faʻamaʻi faʻamaʻi.
