Atazanavir CAS 198904-31-3 Mama ≥99.0% API Falegaosi Anti-HIV HIV-1 Protease Inhibitor

Atazanavir (CAS 198904-31-3) o se antiretroviral, tala ma malosi azapeptide vailaʻau o le protease inhibitor (PI) vasega.O loʻo faʻatau atu i lalo o le igoa tau fefaʻatauaʻiga Reyataz.E pei o isi vailaʻau faʻamaʻi, e faʻaaogaina e togafitia ai faʻamaʻi pipisi o le tagata immunodeficiency virus type 1 (HIV-1) protease enzyme faʻatasi ai ma le faʻalavelave tumau Ki o le 66 nmol/L ma faʻalavelaveina ai le toe faʻafoʻiina o le HIV-1 ma le 50% aoga faʻamalosi EC50 amata mai. 2.6 i le 5.3 nmol/L.Atazanavir o loʻo fusifusia i le HIV-1 protease e puipuia ai le vaeluaga o gag ma gag-pol polyproteins, lea e mafua ai le faʻavaeina o virions le matua i sela o loʻo aʻafia i le HIV-1.O le Atazanavir e ese le C-2 symmetric chemical structure ma e masani ona sili atu le malosi o le antiretroviral i faʻamaʻi HIV eseese pe a faʻatusatusa i isi inhibitors protease, e aofia ai Indinavir, Nelfinavir, Ritonavir, Saquinavir ma Amprenavir.Atazanavir e ese mai isi PI e mafai ona tuʻuina atu i le aso e tasi ma e itiiti sona aʻafiaga i le lipid profile o le maʻi.E pei o isi protease inhibitors, e faʻaaogaina faʻatasi ma isi vailaʻau HIV.Atazanavir o se fa'ama'i fa'atosina ole HIV protease ole azapeptide.Antiviral.E ave i le gutu faatasi i le aso.