Atazanavir CAS 198904-31-3 Mama ≥99.0% API Falegaosi Anti-HIV HIV-1 Protease Inhibitor
Tuuina atu ma le mama maualuga ma le mautu lelei
Igoa Vailaau: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Atazanavir |
Synonyms | BMS-232632 |
Numera CAS | 198904-31-3 |
CAT Numera | RF-API70 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C38H52N6O7 |
Molecular Weight | 704.86 |
Lisi Lisi | 207.0~209.0 ℃ |
Solubility | Solu i le DMSO;E le mafai ona solu i le Vai |
Teuga umi | Taofi umi i le -20℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e |
Fomu | Fa'avae Sa'oloto |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Le mama A | ≤0.10% |
Le mama B | ≤0.10% |
Le mama nofofua | ≤0.20% |
Aofa'i Fa'aleaga | ≤1.0% |
Fa'amama/su'esu'ega Metotia | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | HIV-1 Protease Inhibitor Anti-HIV |
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
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Atazanavir (CAS 198904-31-3) o se antiretroviral, tala ma malosi azapeptide vailaʻau o le protease inhibitor (PI) vasega.O loʻo faʻatau atu i lalo o le igoa tau fefaʻatauaʻiga Reyataz.E pei o isi vailaʻau faʻamaʻi, e faʻaaogaina e togafitia ai faʻamaʻi pipisi o le tagata immunodeficiency virus type 1 (HIV-1) protease enzyme faʻatasi ai ma le faʻalavelave tumau Ki o le 66 nmol/L ma faʻalavelaveina ai le toe faʻafoʻiina o le HIV-1 ma le 50% aoga faʻamalosi EC50 amata mai. 2.6 i le 5.3 nmol/L.Atazanavir o loʻo fusifusia i le HIV-1 protease e puipuia ai le vaeluaga o gag ma gag-pol polyproteins, lea e mafua ai le faʻavaeina o virions le matua i sela o loʻo aʻafia i le HIV-1.O le Atazanavir e ese le C-2 symmetric chemical structure ma e masani ona sili atu le malosi o le antiretroviral i faʻamaʻi HIV eseese pe a faʻatusatusa i isi inhibitors protease, e aofia ai Indinavir, Nelfinavir, Ritonavir, Saquinavir ma Amprenavir.Atazanavir e ese mai isi PI e mafai ona tuʻuina atu i le aso e tasi ma e itiiti sona aʻafiaga i le lipid profile o le maʻi.E pei o isi protease inhibitors, e faʻaaogaina faʻatasi ma isi vailaʻau HIV.Atazanavir o se fa'ama'i fa'atosina ole HIV protease ole azapeptide.Antiviral.E ave i le gutu faatasi i le aso.
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