Atazanavir Sulfate CAS 229975-97-7 Mama ≥99.0% API Falegaosi Anti-HIV HIV-1 Protease Inhibitor
Tuuina atu ma le mama maualuga ma le mautu lelei
Igoa Vailaau: Atazanavir Sulfate
CAS: 229975-97-7
HIV-1 Protease Inhibitor
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Atazanavir Sulfate |
Synonyms | BMS-232632 Sulfate |
Numera CAS | 229975-97-7 |
CAT Numera | RF-API71 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C38H52N6O7.H2SO4 |
Molecular Weight | 802.93 |
Lisi Lisi | 195.0~198.0 ℃ |
Solubility | E le mafai ona solu ile Suavai, Solu ile DMSO |
Teuga umi | Taofi umi i le -20℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Sulfate | 12.0~12.5% |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.10% |
Metala mamafa | ≤20ppm |
Le mama nofofua | ≤0.30% |
Aofa'i Fa'aleaga | ≤1.0% |
Fa'amama/su'esu'ega Metotia | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | HIV-1 Protease Inhibitor Anti-HIV |
afifi: Fagu, Ato pepa alumini, Pusa Pusa, 25kg / Paʻu, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
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Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) o se masima masima sulfate o atazanavir lea o se HIV-1 protease inhibitor sili ona filifilia, o le inhibitor protease muamua ua faʻatagaina mo le faʻatonuina i aso uma.Atazanavir Sulfate o se mea faʻapipiʻi ma faʻalavelave ole CYP3A4, ma se faʻalavelave ma faʻaosoina ole P-glycoprotein (P-gp).Atazanavir Sulfate ose SARS-CoV 3CLpro inhibitor ma le IC50 o le 3.49 μM.Atazanavir Sulfate o se azapeptide ma HIV-protease inhibitor lea e faʻaaogaina i le togafitia o faʻamaʻi pipisi o le HIV ma le AIDS faʻatasi ma isi Anti-HIV Agents, ua atiina ae ma faʻalauiloa e Bristol-Myers Squibb (BMS), i lalo ole laisene i le lalolagi atoa mai Novartis, mo togafitiga o fa'ama'i pipisi o le HIV.Atazanavir na faalauiloa i le US e pei o Reyataz™ ia Iulai 2003. Antiviral.Atazanavir ua faʻaalia e sili atu le malosi nai lo le lima faʻamaonia HIV-1 protease inhibitors.O le Atazanavir e faʻagataina le faʻaogaina o le viral Gag ma le Gag-Pol polyproteins i siama faʻamaʻi HIV-1 e ala i le fusifusia i le nofoaga galue o le HIV-1 protease, ma taofia ai le fausiaina o virion matutua.Atazanavir e le o malosi e tetee atu i le HIV-2.