Bicalutamide CAS 90357-06-5 falegaosimea API High Quality Advanced Prostate Cancer

Bicalutamide (CAS: 90357-06-5) o se non-steroidal androgen antagonist, lea e tauva ai le androgen receptor ma le androgen, poloka le faʻaogaina o le androgen, ma faʻalavelaveina le fusifusia o androgens i le okeni taulaʻi.E fusifusia ma le androgen receptor lea e fausia ai le faʻalavelave faʻalavelave, lea e ulu atu i totonu o le nucleoprotein ma tuʻufaʻatasia ma le nucleoprotein, e mafua ai ona taofia le tuputupu aʻe o le tumo.E mafai ona avea o se vaila'au laina muamua mo togafitiga fa'amalolo o le kanesa prostate maualuga.O le Bicalutamide na faʻalauiloaina i Peretania, o lana maketi muamua i le lalolagi atoa, mo le togafitiga o le kanesa prostate maualuga faʻatasi ma le LHRH analog poʻo le taotoga faʻapitoa.O se non-steroidal, peripherally selective antiandrogen, bicalutamide e taofia ai le gaioiga o le dihydrotestosterone ma le testosterone i nofoaga faʻatatau e ala i le faʻatauvaʻa faʻatauvaʻa i le cytosolic androgen receptor.Na lipotia mai na talia lelei e aunoa ma ni aʻafiaga ogaoga cardiovascular ma metabolic ona o le manuia o le leai o soʻo se gaioiga faʻamalosi.O le aoga o le bicalutamide o se monotherapy ua faʻaalia ile falemaʻi.Sa lipotia mai fo'i fua faatatau lelei o tali i le togafitia o le kanesa colorectal, susu, pancreas ma le mama sela laiti.