Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Mama ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate
Tuuina atu le Sitagliptin Phosphate Monohydrate Fesoʻotaʻi Faʻatasi:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Igoa Vailaau | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Synonyms | (R)-Sitagliptin N-Boc-Acid Le mama |
Numera CAS | 486460-00-8 |
CAT Numera | RF-PI1192 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C15H18F3NO4 |
Molecular Weight | 333.31 |
Lisi Lisi | 136.0~138.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Faailoaina e le HPLC | Ole Taimi Fa'atumauina ole Fa'ata'ita'iga e fetaui ma Fa'amaumauga Fa'asinomaga |
Ma'imau ile Fa'amago | ≤0.50% |
Lefulefu Sulphated | ≤0.50% |
Metala mamafa | <20ppm |
Isomer | ≤0.50% |
Mea Fa'atatau | |
Le mama A | ≤0.50% |
So'o se isi mea le mama e tasi | ≤0.50% |
Aofa'i Fa'aleaga | ≤0.50% |
Mama | ≥99.5% (HPLC) |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Vaeluaga ole Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) o se mea taua tele mo le saunia o le sitagliptin.Sitagliptinphosphate o le dipeptidase muamua -IV(DPP-4) inhibitor ua faʻamaonia e le FDA i le 2006. E faʻaaogaina mo togafitiga o le maʻisuka ituaiga II.O loʻo i ai le aʻafiaga o le hypoglycemic pe'ā faʻaaogaina naʻo ia pe faʻatasi foi ma le metformin ma le pioglitazone, ma e saogalemu e ave, faʻafeiloaʻi lelei, ma e itiiti ni aʻafiaga leaga.I le masina o Aukuso 2009, na faʻamaonia ai le vailaʻau e le Iuni a Europa e avea o se vailaʻau muamua mo le togafitiga o le maʻisuka ituaiga 2.Ina ua maeʻa le 2011, ua faʻamaonia e le tasi ma le isi atunuu le tuʻufaʻatasia o le sitagliptin phosphate ma le alpha glycosidase inhibitors poʻo le inisalini.O le Sitagliptin phosphate o le fa'atosina muamua o le dipeptidyl peptidase-IV ua fa'atagaina e le FDA e fa'aaogaina i le togafitiga o le ma'isuka ituaiga 2 i le mamao, i lalo o le igoa tau fefa'ataua'iga Januvia.