Brexpiprazole CAS 913611-97-9 Mama >99.0% (HPLC) API Falegaosi
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl) piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-tasi CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Igoa Vailaau | Brexpiprazole |
Synonyms | OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one |
Numera CAS | 913611-97-9 |
CAT Numera | RF-PI1982 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C25H27N3O2S |
Molecular Weight | 433.57 |
Malosi | 1.245±0.060g/cm3 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Fa'ailoaga | Saunia e IR |
RT | I lalo ole chirality e tatau ona tausisia |
Klorida | E maua ai se tali ole chloride |
Vai | 3.0%~4.5% |
Lisi Lisi | 198.0~202.0 ℃ |
Toega i luga o le mumu | <0.20% |
Metala mamafa | ≤10ppm |
Mea Fa'atatau | |
Le mama o le tagata lava ia | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
EE | >99.0% |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC, fa'amamago) |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Brexpiprazole (CAS: 913611-97-9) o se sui o fualaau faasaina e aoga i togafitiga ma le puipuia o faaletonu o le mafaufau e aofia ai faaletonu CNS.O le Brexpiprazole o se vailaʻau antipsychotic fou lea e avea o se serotonin ® dopamine activity modulator ma ua faʻaalia le aoga o se togafitiga faʻaopoopo i tagata mamaʻi e maua i le maʻi tigaina tele (MDD).Brexpiprazole o loʻo faʻaalia se faʻamatalaga faʻapitoa faʻafomaʻi, galue o se vaega agonist o le serotonin 5-HT1A ma le dopamine D2 faʻafeiloaʻi ma o se faʻalavelave atoa o le 5-HT2A ma le noradrenaline α1B / 2C faʻafeiloaʻi, faʻatasi ai ma le tutusa o le subnanomolar binding affinity.Brexpiprazole na atiaʻe e Otsuka ma Lundbeck, na faʻamaonia i le 2015 e le FDA mo togafitiga o le schizophrenia ma o se togafitiga faʻaopoopo mo le atuatuvale.Brexpiprazole ua manatu lautele e suitulaga i le Otsuka's antipsychotic drug aripiprazole (igoa fefaatauaiga Abilify) na muta lona pateni ia Aokuso 2014.