Brigatinib CAS 1197953-54-0 Mama >99.0% (HPLC)

Fa'amatalaga Puupuu:

Igoa Vailaau: Brigatinib

Synonyms: AP-26113

CAS: 1197953-54-0

Mama: >99.0% (HPLC)

Fa'aaliga: Pa'epa'e i le Pa'epa'e Pa'epa'e

Fa'afeso'ota'i: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

1197953-54-0 -Fa'amatalaga:

Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Brigatinib (AP-26113) (CAS: 1197953-54-0) faʻatasi ai ma tulaga maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau Brigatinib,Please contact: alvin@ruifuchem.com

1197953-54-0 -Meatotino tau vailaau:

Igoa Vailaau Brigatinib
Synonyms AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl)phenyl]-N2-[2-Methoxy-4-[4-(4-Methyl-1-Piperazinyl)-1-Piperidinyl]phenyl]-2,4-Pyrimidinediamine
Tulaga Fa'asoa I Fa'atauga, Gaosiga Fa'apisinisi
Numera CAS 1197953-54-0
Fuafua mole C29H39ClN7O2P
Molecular Weight 584.09 g/mol
Lisi Lisi >203℃(Tes.)
Malosi 1.31±0.10g/cm3
COA & MSDS Avanoa
Amataga Shanghai, Saina
Fa'ailoga Ruifu Chemical

1197953-54-0 -Fa'amatalaga:

Aitema Fa'amatalaga I'uga
Fa'aaliga Pa'epa'e i le Pa'epa'e Pa'epa'e E usitaia
Mama / Suʻesuʻega Metotia >99.0% (HPLC) 99.26%
Max.Le mama nofofua <1.00% 0.25%
Ma'imau ile Fa'amago <1.00% 0.27%
Alaleo Infrared Ia ogatasi ma le Fauga E usitaia
1H NMR Alaleo Ia ogatasi ma le Fauga E usitaia
Fa'ai'uga Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga

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FAQ:

Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

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1197953-54-0 - Fa'amatalaga Lautele:

Brigatinib (AP-26113) (CAS: 1197953-54-0) o se suʻesuʻega laʻititi laʻititi e faʻatatau i togafitiga o le kanesa o loʻo atiaʻe e le ARIAD Pharmaceuticals, Inc. Brigatinib o se vailaʻau faʻaaogaina e togafitia ai le kanesa e taofia ai le epidermal growth factor receptor (EGFR) ma anaplastic lymphoma kinase (ALK).Brigatinib o se agonist filifilia e faasaga i fesuiaiga o le EGFR e ese mai i foliga mutant vao.O le vailaʻau o loʻo faʻaalia ai foi le filifilia e faasaga i le ALK-EML4 fusion gene, o se itu taua o le fesuiaiga o parenchyma mama mama.O le Brigatinib e fa'atonuina mo tagata mama'i e iai ni kenera fa'apitoa ma pe a le tali atu le kanesa o le mama sela (NSCLC) i le pulega ma isi vaila'au.O le Brigatinib o loʻo faʻavasegaina o se iniseti kinase, o lona faiga o gaioiga e aofia ai le taofiofia o le gaioiga o polotini faʻalavelave e faʻaleleia ai le faʻateleina o sela o le kanesa.

1197953-54-0 - Fa'ailoga:

Brigatinib (CAS: 1197953-54-0) o loʻo faʻatonuina mo tagata mamaʻi e iai ituaiga faʻapitoa ole NSCLC ua sosolo atu i vaega eseese o le tino i tagata na faia muamua togafitiga ma isi vailaʻau o le kanesa e pei ole Crizotinib, ma ua sili atu le leaga o latou tulaga. pe fa'ailoa mai ai ni fa'ailoga laiti o le fa'aleleia.O lo'o fa'ata'ita'iina i lalo ole su'esu'ega mo lona aoga ile kanesa ole mama sela (NSCLC) lea o lo'o fa'agaoioia ai le ALK ma e masani ona tupu suiga ole EGFP.

1197953-54-0 - Talosaga:

Brigatinib (AP-26113) (CAS: 1197953-54-0) o se faʻalavelave fou o le tyrosine kinase, faʻaalia le aoga tele i le ALK + metastatic NSCLC.I le aso 30 o Aokuso, 2016, na tuʻuina atu ai e le United States FDA le bugtinib e avea ma togafitiga faʻapitoa ma se vailaʻau seasea mo le ALK + NSCLC i tagata mamaʻi ua atiaʻe pe le mafai ona faʻafeiloaʻi Crizotinib, o le uluai augatupulaga ALK + NSCLC togafitiga.Tu'u le fa'amuamua i le lisi o le iloiloga o talosaga ma fa'ataga le tu'uina atu o fa'amaumauga o talosaga i se faiga fa'asolosolo.Na faamaonia e le FDA le Bugtinib ia Aperila 28, 2017, i lalo o le igoa tau fefaʻatauaʻiga Alunbrigtm.

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