Candesartan Cilexetil CAS 145040-37-5 Mama >99.0% (HPLC) API Fa'aaliga Fa'aalia Ata

Candesartan Cilexetil CAS 145040-37-5 Mama >99.0% (HPLC) API Falegaosi

Fa'amatalaga Puupuu:

Igoa vaila'au: Candesartan Cilexetil

CAS: 145040-37-5

Mama: >99.0% (HPLC)

Fa'aaliga: Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e

Ose Angiotensin II Receptor Antagonist Filifilia

API Tulaga Maualuga, Gaosiga Fa'apisinisi

E-Mail: alvin@ruifuchem.com

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Fa'amatalaga:

Ruifu Chemical Supply Candesartan Cilexetil Intermediate With High Purity
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Meatotino tau vailaau:

Igoa Vailaau	Candesartan Cilexetil
Synonyms	TCV-116;1-((((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo[d]imidazole-7-Carboxylate
Numera CAS	145040-37-5
CAT Numera	RF-PI1891
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole	C33H34N6O6
Molecular Weight	610.66
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e
Fa'ailoga HPLC	O le taimi fa'atumauina o le tumutumu tele i le chromatogram o le fa'ata'ita'iga e fetaui ma lena i le chromatogram maua ma le tulaga masani.
Faailoaina IR	IR infrared absorption spectrum e tutusa ma le Candesartan Cilexetil reference standard
Malamalama ma Valivali Fofo	Ole fofo ile chloroform ile 5% e manino ma leai se lanu
Mama / Suʻesuʻega Metotia	>99.0% (HPLC)
Lisi Lisi	155.0~160.0 ℃
Ma'imau ile Fa'amago	<0.30%
Toega i luga o le mumu	<0.10%
Metala mamafa	<10ppm
Arsenic (As)	<1ppm
Tufatufaina o le Lapalapala	90% <30 μm
Oona Fa'aleaga	e le HPLC
Ethyl Candesartan	<0.15%
Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
So'o se Fa'aleaga Le Malamalama	<0.15%
Aofa'i Fa'aleaga	<0.60%
Su'ega ile Potentiometry	99.0~101.0% o le C33H34N6O6, fuafuaina i luga ole mea anhydrous
Organic Volatile Le mama
Methano	<0.30%
Ethanol	<0.50%
Dietil Eteru	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Microbiological Contarnination
Aofa'i Aerobic Microbial Faitau	<1000cfu/g
Limu & Faafefete	<100cfu/g
E.Coli	Toesea
Salmonella	Toesea
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	API;Su'i fa'ama'i toto

Paket & Teuina:

afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

Tulaga lelei:

FAQ:

Talosaga:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) o le angiotensin II receptor antagonist ma IC50 o le 0.26 nM, faʻaaogaina i le togafitiga o le toto maualuga.Candesartan ose angiotensin-receptor blocker (ARB) e mafai ona faʻaaogaina naʻo ia poʻo isi vailaʻau e togafitia ai le toto maualuga.O loʻo tuʻuina tautala e pei o le prodrug, candesartan cilexetil, lea e vave ona liua i lona metabolite malosi, candesartan, i le taimi o le absorption i le gastrointestinal tract.Candesartan e faʻaititia le toto maualuga e ala i le faʻafefe o le renin-angiotensin-aldosterone system (RAAS);e tauva ma le angiotensin II mo le fusia i le ituaiga-1 angiotensin II receptor (AT1) subtype ma puipuia ai le maualuga o le toto maualuga aafiaga o le angiotensin II.E le pei o le angiotensin-converting enzyme (ACE) inhibitors, ARBs e leai ni a'afiaga leaga o le tale mago.Candesartan e mafai ona faʻaaogaina e togafitia ai le toto maualuga, toto maualuga faʻapitoa, hypertrophy ventricular agavale ma nephropathy o le maʻisuka.E mafai foi ona faʻaaogaina e fai ma sui sui mo togafitiga o le fatu fatu, systolic dysfunction, myocardial infarction ma faʻamaʻi alatoto.