Capecitabine CAS 154361-50-9 Mama 98.0%~102.0% API Tulaga Maualuga
Fa'atauga Fa'atauga Capecitabine Feso'ota'i Vaitaimi:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
| Igoa Vailaau | Capecitabine |
| Numera CAS | 154361-50-9 |
| CAT Numera | RF-API08 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C15H22FN3O6 |
| Molecular Weight | 359.35 |
| Lisi Lisi | 110.0~121.0 ℃ |
| Tulaga Va'a | I lalo ole Temperature Ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'u Pa'epa'e |
| Fa'ailoaga | Ole fa'ata'ita'iga ole Fusi ole IR e tatau ona fetaui ma alaleo ole tulaga fa'asino |
| Fa'ailoaga | HPLC: Ole taimi fa'atumauina ole pito maualuga ole fa'ata'ita'iga fofo e tatau ona fetaui ma le tulaga fa'asino. |
| Mama | 98.0% ~ 102.0% (i luga o le anhydrous ma solvent-saoloto faavae) |
| Vaitaimi Mata | +96.0°~+100° |
| Susū (KF) | ≤0.30% |
| Toega ile mu | ≤0.10% |
| Metala mamafa | ≤20ppm |
| Feso'ota'i Le mama A | ≤0.30% |
| Feso'ota'i Le mama B | ≤0.30% |
| Feso'ota'i Le mama C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Nofofua Le fa'amamafaina le mama | ≤0.10% |
| Aofa'i Le Fa'amamafaina | ≤0.50% |
| Aofa'i Fa'aleaga | ≤1.5% |
| Solvents totoe (GC) | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Toluene | ≤800ppm |
| Pyridine | ≤200ppm |
| Hexane | ≤290ppm |
| Aofa'i Aerobic Microbial Faitau | ≤200cfc/g |
| Faafefete ma Limu Faitau | ≤50cfc/g |
| Tulaga Su'ega | United States Pharmacopoeia (USP) |
| Fa'aoga | Kanesa ole Susu Metastatic |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Capecitabine (CAS: 154361-50-9) o se ituaiga fou o vailaʻau oral fluorinated pyrimidine.Capecitabine na atiae e Roche Pharmaceuticals, ma o lona igoa faapisinisi o Xeloda.Capecitabine e mafai ona suia i totonu o le vivo i le 5-FU, o se anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate vailaʻau e faʻatatau i sela o le kanesa e taofia ai le vaevaeina o sela ma faʻalavelaveina le RNA ma le faʻasologa o le protein.O ona a'afiaga e feso'ota'i tele i le maualuga o le fa'aaliga o le enzyme TP i le neoplastic tissue ma le DPD enzyme in vivo expression.E talafeagai e fai ma isi togafitiga mo tagata mama'i o le susu muamua po'o metastatic e le'i tali atu i vaila'au paclitaxel po'o anthracycline.I le avea ai o se vailaʻau faʻamaʻi, e masani ona faʻaaogaina e togafitia ai le kanesa o le susu muamua poʻo le metastatic, faʻapea foʻi ma togafitiga mo le kanesa o le mama sela, kanesa pancreatic, kanesa o le manava, kanesa rectal, kanesa colon, kanesa gastric, ma isi tuma malosi. .
