Carvedilol Phosphate Hemihydrate CAS 610309-89-2 Mama>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) faʻatasi ai ma le maualuga.E mafai e Ruifu ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo maua.Fa'atau Carvedilol Phosphate Hemihydrate,Please contact: alvin@ruifuchem.com
Feso'ota'i Intermediates o Carvedilol
Igoa Vailaau | Carvedilol Phosphate Hemihydrate |
Synonyms | BM 14190 Phosphate Hemihydrate;1-(9H-Carbazol-4-yloxy)-3-[2-(2-Methoxyphenoxy)ethylamino]propan-2-olphosphoricacidhydrate |
Tulaga Fa'asoa | E tele |
Numera CAS | 610309-89-2 |
Fuafua mole | C24H26N2O4.H3PO4.0.5H2O |
Molecular Weight | 513.47 g/mol |
COA & MSDS | Avanoa |
Fa'ailoga | Ruifu Chemical |
Aitema | Tulaga Fa'atonu | I'uga |
Fa'aaliga | Pa'u tioata Pa'epa'e | E usitaia |
Vai saunia e Karl Fischer | ≤2.50% | E usitaia |
Mea Fa'atatau | ≤0.50% | E usitaia |
Metala mamafa (Pb) | ≤10ppm | <10ppm |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) | 99.5% |
Alaleo Infrared | E tusa ma le Fauga | E usitaia |
Fa'ai'uga | Ua fa'ata'ita'iina le oloa ma fa'amalieina fa'amatalaga |
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Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) o se filifiliga poloka poloka α1-receptor ma le le filifilia β-receptor blocker, leai ni vailaʻau malosi Sympathimetic, bioavailability o 10 ~ 47%, e le afaina i meaʻai, le aafiaga ile α1 -receptor e matua maualalo ifo nai lo β1-ma β2-receptor, o le malosi o le fua faatatau o le β 1-ma le β2-receptor poloka o le 1:10 ~ 1:100.O le aʻafiaga o le β1-receptor blockade e tusa ma le 1/2 o labetalol, ma o lona α1 poloka e sili atu le vaivai nai lo le prazosin.E mafai ona fa'ateteleina a'a toto, fa'aitiitia le tete'e o le toto, fa'apalapala ala fatu ma fatu, ma fa'aitiitia le mamafa o le pulmonary wedge.O loʻo i ai se aafiaga puipuia manino i luga o le myocardial hypoxia ma le myocardial manua e mafua mai i le myocardial infarction, lea e mafai ona fesoʻotaʻi ma le poloka o le β-receptor, lea e mafai ona faʻaitiitia ai le faʻaitiitia o le myocardial glycogen ma le faateleina o le pH, ma faʻaitiitia le tele o le infarct.
O le Carvedilol Phosphate Hemihydrate e faʻaaogaina e togafitia ai le toto maualuga ma e mafai ona faʻaaogaina naʻo ia pe faʻatasi ma isi vailaʻau faʻamalosi (aemaise lava thiazide diuretics).Mo fa'ailoga fa'ama'i fa'aletonu fatu.
Carvedilol Phosphate Hemihydrate o se β / α-1 e le filifilia le talipupuni poloka.Carvedilol taofia le lipid peroxidation ma se IC50 o le 5 μM.Carvedilol o se vailaʻau antihypertensive tele-faamoemoega e mafai ona suʻesuʻeina le angina pectoris ma le faʻaletonu o le fatu.