Daclatasvir Dihydrochloride Intermediate CAS 1007882-23-6 Mama >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Daclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) faʻatasi ai ma le maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, laʻititi ma tele aofaʻi avanoa.Fa'atau Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
| Synonyms | Daclatasvir Intermediate Ⅱ;Dacaltasvir Intermediate 02;Daclatasvir T-Butyl Ester;Bis(2-Methyl-2-Propanyl) (2S,2'S)-2,2'-[4,4'-Biphenyldiylbis(1H-Imidazole-4,2-diyl)]di(1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2′-([1,1′-Biphenyl]-4,4′-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate);(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl)bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Daclatasvir Le mama 4 |
| Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
| Numera CAS | 1007882-23-6 |
| Fuafua mole | C40H51ClN8O6 |
| Molecular Weight | 775.35 g/mol |
| Fa'apuna | 890.2±65.0℃ ile 760 mmHg |
| Malosi | 1.220±0.06 g/cm3 |
| COA & MSDS | Avanoa |
| Amataga | Shanghai, Saina |
| Vaega | Vaitaimi ole Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga | I'uga |
| Fa'aaliga | Samasama moli i le Pata Samasama | Pata Samasama Malamalama |
| Ma'imau ile Fa'amago | <1.00% | 0.65% |
| Avanoa Tasi Tumaoti | <1.00% | 0.45% |
| Aofa'i Fa'aleaga | <2.00% | 1.24% |
| Mama / Suʻesuʻega Metotia | >98.0% (HPLC) | 98.76% |
| Alaleo Infrared | O gatasi ma le Fauga | E usitaia |
| 1H NMR Alaleo | O gatasi ma le Fauga | E usitaia |
| Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
| Fa'atatauga | Vaitaimi ole Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
afifi:Fa'ato'aga Fa'alili, Ato pepa alumini, 25kg/Cardboard Drum, pe tusa ai ma mana'oga o tagata fa'atau.
Tulaga teuina:Taofi mau le koneteina ma teu i totonu o se faleteuoloa malulu, mago ma lelei le savili mai mea e le fetaui.Puipui mai le malamalama ma le susu.
Va'a:Tu'u atu ile lalolagi atoa ile ea, ile FedEx / DHL Express.Tuuina atu vave ma faatuatuaina tiliva.
Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Tausaga Aafiaga?E sili atu nai lo le 15 tausaga o le poto masani i le gaosiga ma le auina atu i fafo o le tele o tulaga maualuga o vailaʻau faʻapitoa poʻo vailaʻau lelei.
Maketi Autu?Faʻatau atu i maketi i totonu o le atunuʻu, Amerika i Matu, Europa, Initia, Korea, Iapani, Ausetalia, ma isi.
Tulaga lelei?Tulaga maualuga, tau taugofie, auaunaga faʻapolofesa ma lagolago faʻapitoa, vave tuʻuina atu.
Tulaga leleiFaamautinoaga?Fa'atonuga lelei faiga.O meafaigaluega faʻapitoa mo suʻesuʻega e aofia ai le NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Fa'ata'ita'iga?O le tele o oloa e maua ai faʻataʻitaʻiga e leai se totogi mo le iloiloga lelei, o tau o felauaiga e tatau ona totogi e tagata faʻatau.
Fale Su'etusi?Fa'afeiloa'i su'etusi falegaosimea.Fa'amolemole fai se taimi vave.
MOQ?Leai MOQ.Laititi oka e talia.
Taimi Tiliva? Afai o loʻo i totonu o faʻatauga, e tolu aso e faʻamaonia le tuʻuina atu.
Felauaiga?E ala ile Express (FedEx, DHL), ile Air, ile Sea.
Pepa?A maeʻa le faʻatau atu auaunaga: COA, MOA, ROS, MSDS, ma isi mea e mafai ona tuʻuina atu.
Tulaga Fa'apitoa?E mafai ona tu'uina atu au'aunaga tu'ufa'atasiga fa'apitoa e fetaui lelei ma au su'esu'ega mana'oga.
Tulaga Totogi?Proforma invoice o le a lafo muamua pe a maeʻa le faʻamaoniga o le poloaiga, faʻapipiʻi a matou faʻamatalaga faletupe.Totogi e le T / T (Telex Transfer), PayPal, Western Union, ma isi.
Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) ose vaeluaga ole Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir (Daklinza) ua maua "toe iloilo faamuamua" tulaga, tuufaatasia ma Sorafenib mo le togafitiga o genotype III tagata matutua maʻi ma hepatitis C. Daklinza ua avea ma uluai fualaau faasaina ua faamaonia o le aoga i le togafitiga o genotype III hepatitis C virus. faʻamaʻi e aunoa ma le faʻatasi ma le interferon poʻo le ribavirin.Interferon ma Ribavirin o ni vaila'au e lua ua fa'atagaina e le FDA mo le togafitia o fa'ama'i pipisi o le hepatitis C.O le Hepatitis C o se fa'ama'i viral e mafai ona mafua ai le fula o le ate, e mafua ai le fa'aitiitia o le ate po'o le fa'aletonu o le ate.O le tele o tagata mama'i e maua i le hepatitis C e leai ni fa'ailoga se'iloga ua aliali mai le fa'aleagaina o le ate, ma e ono tele tausaga e alu ai.I le lalolagi atoa, genotype III hepatitis C o le genotype lona lua sili ona taatele o le hepatitis C ina ua mavae le genotype 1 hepatitis C ma ua manatu o se tasi o faamai sili ona refractory genotype.Daklinza o se pan-genotype NS5A replication faʻalavelave faʻalavelave faʻalavelave, faʻatasi ai ma le aoga o le faʻasaina o le RNA replication ma viral faʻapotopotoga, lua faʻamaʻi antiviral.Mo suʻesuʻega in vitro, ua faʻaalia e Daklinza le i ai o le anti-viral e faasaga i le genotype 1 ~ 6 hepatitis C virus.Daklinza o loʻo faʻatasi ma se lapataiga o le tuʻufaʻatasia o amiodarone, Daklinza ma Sofosbuvir e mafai ona mafua ai le faʻaitiitia o le fatu fatu.Daklinza o se laulau tuʻu gutu ma le fua fautuaina o le 60 mg mo le 1 taimi / d, faʻatasi ma Sofosbuvir mo le aofaʻi o le 12 vaiaso.
Kamupani su'esu'e ma atina'e: Bristol-Myers Squibb.
Tusi Pateni: WO 2008021927A2 (Aokuso 9, 2007).
Taimi o maketi: Iulai 24, 2015 lisiina i le Iunaite Setete, igoa tau fefaʻatauaʻiga Daklinza.
Fa'ailoga: Fa'aaogā fa'atasi ma le Sofosbuvir mo le togafitia o fa'ama'i fa'ama'i pipisi o le hepatitis C (HCV) genotype 3.
Faiga o gaioiga: HCV nonstructural protein 5A (NS5A) inhibitors.A'afiaga leaga: tiga o le ulu ma le vaivai.
Fuafuaga ma faʻamatalaga: Papamaʻa, 30 ma le 60mg.
