2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel Intermediate Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o le 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) faʻatasi ai ma le maualuga, vaeluaga ole Perampanel (CAS: 380917-97-5).Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau Perampanel intermediates, Please contact: alvin@ruifuchem.com
| Igoa Vailaau | 2-Cyanophenylboronic Acid 1,3-Propanediol Ester |
| Synonyms | 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2-(1,3,2-Dioxaborinan-2-yl)benzonitrile |
| Numera CAS | 172732-52-4 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C10H10BNO2 |
| Molecular Weight | 187.01 |
| Lisi Lisi | 46.0~51.0 ℃ (malamalama) |
| Malosi | 1.13±0.10g/cm3 |
| Solubility | Solu i le Methanol |
| Maumau | Hygroscopic |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e e o'o i le Pa'u Samasama Malamalama i Crystal |
| Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
| Ma'imau ile Fa'amago | <0.50% |
| Toega i luga o le mumu | <0.20% |
| Le mama nofofua | <0.50% |
| Aofa'i Fa'aleaga | <1.00% |
| Metala mamafa (pei o le Pb) | <20ppm |
| Tulaga Su'ega | Enterprise Standard |
| Fa'aoga | Intermediate of Perampanel (CAS: 380917-97-5) |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
Fa'ailoga Mata'utia Xi - Itaita
Tulaga lamatia
R20/21/22 - E afaina pe a manava, pe a pa'u ma pe a folo.
R36/37/38 - Fa'aitaita'i i mata, faiga manava ma le pa'u.
Fa'amatalaga Saogalemu
S26 - Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga faafoma'i.
S36/37/39 - Fai ofu puipui talafeagai, totigilima ma mata/mata.
UN IDs 3439
WGK Siamani 3
TSCA Nu
Mata'utia Fa'amatalaga Fa'aitaita
2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) o loʻo faʻaaogaina i le tuʻufaʻatasiga o Perampanel (CAS: 380917-97-5), o le AMPA receptor antagonist.O Perampanel (laisene i le 2012) o le tolu-tupulaga AED ua lauiloa ma le igoa faʻapitoa o Fycompa® (Eisai, Hatfield) i Peretania ma Banzel® (Eisai, Hatfield) i Amerika.Ia Oketopa 2012, na faʻamaonia ai e le US FDA le perampanel mo le togafitia o faʻalavelave faʻafuaseʻi i tagata gasegase epileptic e le itiiti ifo i le 12 tausaga.O Perampanel o le muamua AMPA e faʻafeiloaʻi faʻalavelave e maua le faʻamaoniga a le FDA o se AED.AMPA glutamate receptors e maua muamua ile postsynaptic neurons ile faiʻai.I le avea ai o se tagata fa'atauva'a, e le fa'atauva'a a le AMPA, o le parampanel e taofia ai le tatalaina o alalaupapa ion ma fa'aitiitia ai le fa'atupuina o gaioiga.O Perampanel na faʻamaonia e le European EMA ma le US FDA ia Iulai ma Oketopa 2012, e faʻaaogaina mo togafitiga faʻapitoa o tagata mamaʻi e maua i se vaega faoa faamalosi i luga o le 12 tausaga ma le leai foi o se faoa faamalosi lona lua.I le aso 22 o Iuni, 2015, na faʻasalalau ai e Eisai ua faʻamaonia e le US FDA le faʻalauteleina o le faʻamaoniga o le Pirenparanide hydrate (Fycompa) e avea o se togafitiga faʻapitoa mo faʻamaʻi tonic-clonic muamua i tagata mamaʻi epilepsy 12 tausaga ma luga atu.
