CAS 177036-94-1 Mama >99.0% (HPLC) API Falegaosi Ma'a Maualuga
Sapalai Pisinisi (CAS: 177036-94-1) Faiga Fa'atatau:
CAS: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0
Igoa Vailaau | (S)-2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-Methoxy-3,3-Diphenylpropionic Acid |
Synonyms | (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid |
Numera CAS | 177036-94-1 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C22H22N2O4 |
Molecular Weight | 378.43 |
Ta'amilosaga Fa'apitoa [α]D20 | +170.0° i le +176.0° (C=0.5, MeOH) |
Lisi Lisi | 172.0~178.0℃(Tes.) |
Solubility | E matua solu i le Methanol;Solu i le Ethanol, Acetone;E le mafai ona solu i le Vai |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
Fa'ailoaga | HPLC;NMR;LC-MS |
Mea Fa'atatau | |
Le mama o le tagata lava ia | ≤0.50% |
Aofa'i Fa'aleaga | <1.00% |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Vailaau Fa'atekonolosi |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
(CAS: 177036-94-1) APIose fili endothelin-A (ETA) e tali atu i le tali fa'afeiloa'i ua fa'aofiina mo togafitiga tu'ugutu o tagata mama'i e maua i le toto maualuga o le pulmonary arterial (PAH), e fa'aleleia ai le malosi o le fa'amalositino ma fa'atuai ai le leaga o le falema'i.O le PAH ose fa'ama'i e le masani ai o la'au laiti o le pulmonary e fa'aalia e ala i le fa'atuputeleina ma le toe fa'afouina, e mafua ai le fa'atuputeleina o le fa'atupuina o le malosi o le pulmonary vascular resistance ma le mamafa o le pulmonary arterial, ma mulimuli ane, fa'aletonu ventricular taumatau ma le oti vave.O faʻamaoniga muamua o le PAH e aofia ai le faʻasolosolo malie o le manava, vaivai, tatavale, edema, ma le matapogia.Endothelin-1 (ET-1), o se vasoconstrictor malosi ma muso lamolemole mitogen, o se sao taua i le faatelevaveina o le maʻi, ma o ona aʻafiaga e faʻasalalau e ala i le faʻagaoioia o le ETA ma le ETB receptors.Ia Iuni o le 2007, na tu'uina atu ai e le FDA le fa'atagaga (CAS: 177036-94-1) API mo togafitiga fa'atasi ile aso ole PAH.